1ej6
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(New page: 200px<br /><applet load="1ej6" size="450" color="white" frame="true" align="right" spinBox="true" caption="1ej6, resolution 3.6Å" /> '''Reovirus core'''<br /...)
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Revision as of 11:55, 20 November 2007
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Reovirus core
Overview
The reovirus core is an assembly with a relative molecular mass of 52, million that synthesizes, modifies and exports viral messenger RNA., Analysis of its structure by X-ray crystallography shows that there are, alternative, specific and completely non-equivalent contacts made by, several surfaces of two of its proteins; that the RNA capping and export, apparatus is a hollow cylinder, which probably sequesters its substrate to, ensure completion of the capping reactions; that the genomic, double-stranded RNA is coiled into concentric layers within the particle;, and that there is a protein shell that appears to be common to all groups, of double-stranded RNA viruses.
About this Structure
1EJ6 is a Protein complex structure of sequences from Reovirus sp. with ZN as ligand. Full crystallographic information is available from OCA.
Reference
Structure of the reovirus core at 3.6 A resolution., Reinisch KM, Nibert ML, Harrison SC, Nature. 2000 Apr 27;404(6781):960-7. PMID:10801118
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