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1c10

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[[Image:1c10.gif|left|200px]]
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{{STRUCTURE_1c10| PDB=1c10 | SCENE= }}
{{STRUCTURE_1c10| PDB=1c10 | SCENE= }}
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'''CRYSTAL STRUCTURE OF HEW LYSOZYME UNDER PRESSURE OF XENON (8 BAR)'''
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===CRYSTAL STRUCTURE OF HEW LYSOZYME UNDER PRESSURE OF XENON (8 BAR)===
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==Overview==
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X-ray diffraction is used to study the binding of xenon and krypton to a variety of crystallised proteins: porcine pancreatic elastase; subtilisin Carlsberg from Bacillus licheniformis; cutinase from Fusarium solani; collagenase from Hypoderma lineatum; hen egg lysozyme, the lipoamide dehydrogenase domain from the outer membrane protein P64k from Neisseria meningitidis; urate-oxidase from Aspergillus flavus, mosquitocidal delta-endotoxin CytB from Bacillus thuringiensis and the ligand-binding domain of the human nuclear retinoid-X receptor RXR-alpha. Under gas pressures ranging from 8 to 20 bar, xenon is able to bind to discrete sites in hydrophobic cavities, ligand and substrate binding pockets, and into the pore of channel-like structures. These xenon complexes can be used to map hydrophobic sites in proteins, or as heavy-atom derivatives in the isomorphous replacement method of structure determination.
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(as it appears on PubMed at http://www.pubmed.gov), where 9443341 is the PubMed ID number.
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{{ABSTRACT_PUBMED_9443341}}
==About this Structure==
==About this Structure==
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[[Category: Hydrophobic cavity]]
[[Category: Hydrophobic cavity]]
[[Category: Xenon complex]]
[[Category: Xenon complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 12:12:15 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 20:03:36 2008''

Revision as of 17:03, 30 June 2008

Image:1c10.png

Template:STRUCTURE 1c10

CRYSTAL STRUCTURE OF HEW LYSOZYME UNDER PRESSURE OF XENON (8 BAR)

Template:ABSTRACT PUBMED 9443341

About this Structure

1C10 is a Single protein structure of sequence from Gallus gallus. Full crystallographic information is available from OCA.

Reference

Exploring hydrophobic sites in proteins with xenon or krypton., Prange T, Schiltz M, Pernot L, Colloc'h N, Longhi S, Bourguet W, Fourme R, Proteins. 1998 Jan;30(1):61-73. PMID:9443341

Page seeded by OCA on Mon Jun 30 20:03:36 2008

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