1co4

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[[Image:1co4.gif|left|200px]]
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{{STRUCTURE_1co4| PDB=1co4 | SCENE= }}
{{STRUCTURE_1co4| PDB=1co4 | SCENE= }}
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'''SOLUTION STRUCTURE OF A ZINC DOMAIN CONSERVED IN YEAST COPPER-REGULATED TRANSCRIPTION FACTORS'''
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===SOLUTION STRUCTURE OF A ZINC DOMAIN CONSERVED IN YEAST COPPER-REGULATED TRANSCRIPTION FACTORS===
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==Overview==
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The three dimensional structure of the N-terminal domain (residues 1-42) of the copper-responsive transcription factor Amtl from Candida glabrata has been determined by two-dimensional 1H-correlated nuclear magnetic resonance (NMR) methods. The domain contains an array of zinc-binding residues (Cys-X2-Cys-X8-Cys-X-His) that is conserved among a family of Cu-responsive transcription factors. The structure is unlike those of previously characterized zinc finger motifs, and consists of a three-stranded antiparallel beta-sheet with two short helical segments that project from one end of the beta-sheet. Conserved residues at positions 16, 18 and 19 form a basic patch that may be important for DNA binding.
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(as it appears on PubMed at http://www.pubmed.gov), where 9665167 is the PubMed ID number.
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{{ABSTRACT_PUBMED_9665167}}
==About this Structure==
==About this Structure==
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1CO4 is a [[Single protein]] structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CO4 OCA].
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1CO4 is a [[Single protein]] structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CO4 OCA].
==Reference==
==Reference==
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[[Category: Metal regulation]]
[[Category: Metal regulation]]
[[Category: Metallothionein]]
[[Category: Metallothionein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 12:56:12 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 21:00:35 2008''

Revision as of 18:00, 30 June 2008

Image:1co4.png

Template:STRUCTURE 1co4

SOLUTION STRUCTURE OF A ZINC DOMAIN CONSERVED IN YEAST COPPER-REGULATED TRANSCRIPTION FACTORS

Template:ABSTRACT PUBMED 9665167

About this Structure

1CO4 is a Single protein structure. Full experimental information is available from OCA.

Reference

Solution structure of a zinc domain conserved in yeast copper-regulated transcription factors., Turner RB, Smith DL, Zawrotny ME, Summers MF, Posewitz MC, Winge DR, Nat Struct Biol. 1998 Jul;5(7):551-5. PMID:9665167

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