1cyi

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{{STRUCTURE_1cyi| PDB=1cyi | SCENE= }}
{{STRUCTURE_1cyi| PDB=1cyi | SCENE= }}
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'''CYTOCHROME C6'''
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===CYTOCHROME C6===
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==Overview==
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The molecular structure of cytochrome c6 from the green alga Chlamydomonas reinhardtii has been determined from two crystal forms and refined to 1.9 A resolution. The two crystal forms are likely the result of different levels of post-translational modification of the protein. This is the first report of a high-resolution structure of a chloroplast-derived class I c-type cytochrome. The overall fold is similar to that of other class I c-type cytochromes, consisting of a series of alpha-helices and turns that envelop the heme prosthetic group. There is also a short two-stranded anti-parallel beta-sheet in the vicinity of the methionine axial ligand to the heme; this region of the molecule is formed by the most highly conserved residues in c6-type cytochromes. Although class I c-type cytochromes are assumed to function as monomers, both crystal forms of cytochrome c6 exhibit oligomerization about the heme crevice that is, in part, mediated by the short anti-parallel beta-sheet. The functional significance of this oligomerization is supported by the appearance of similar interfaces in other electron transfer couples, HPLC and light-scattering data, and is furthermore consistent with kinetic data on electron transfer reactions of c6-type cytochromes.
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{{ABSTRACT_PUBMED_7623381}}
==About this Structure==
==About this Structure==
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[[Category: Chlamydomona]]
[[Category: Chlamydomona]]
[[Category: Photosynthesis]]
[[Category: Photosynthesis]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 13:14:51 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 21:48:07 2008''

Revision as of 18:48, 30 June 2008

Image:1cyi.png

Template:STRUCTURE 1cyi

CYTOCHROME C6

Template:ABSTRACT PUBMED 7623381

About this Structure

1CYI is a Single protein structure of sequence from Chlamydomonas reinhardtii. Full crystallographic information is available from OCA.

Reference

The structure of chloroplast cytochrome c6 at 1.9 A resolution: evidence for functional oligomerization., Kerfeld CA, Anwar HP, Interrante R, Merchant S, Yeates TO, J Mol Biol. 1995 Jul 28;250(5):627-47. PMID:7623381

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