1d5v

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[[Image:1d5v.gif|left|200px]]
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{{STRUCTURE_1d5v| PDB=1d5v | SCENE= }}
{{STRUCTURE_1d5v| PDB=1d5v | SCENE= }}
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'''SOLUTION STRUCTURE OF THE FORKHEAD DOMAIN OF THE ADIPOCYTE-TRANSCRIPTION FACTOR FREAC-11 (S12)'''
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===SOLUTION STRUCTURE OF THE FORKHEAD DOMAIN OF THE ADIPOCYTE-TRANSCRIPTION FACTOR FREAC-11 (S12)===
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==Overview==
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Transcription factors of the forkhead type share a highly conserved DNA-binding domain of about 100 amino acid residues. FREAC-11, expressed in adipocytes, belongs to this class. Here, we report on NMR studies that established the three-dimensional structure of the FREAC-11, DNA-binding domain. Although apparent similarities to the structures of other members within the forkhead family are observed, the structure also reveals some remarkable differences. Along with the complementary dynamics, the data provide insight into the fundamentals of sequence specificity within a highly conserved motif.
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(as it appears on PubMed at http://www.pubmed.gov), where 10669593 is the PubMed ID number.
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{{ABSTRACT_PUBMED_10669593}}
==About this Structure==
==About this Structure==
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1D5V is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D5V OCA].
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1D5V is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D5V OCA].
==Reference==
==Reference==
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[[Category: Dna-recognition helix]]
[[Category: Dna-recognition helix]]
[[Category: Winged helix]]
[[Category: Winged helix]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 13:28:59 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 22:29:55 2008''

Revision as of 19:29, 30 June 2008

Image:1d5v.png

Template:STRUCTURE 1d5v

SOLUTION STRUCTURE OF THE FORKHEAD DOMAIN OF THE ADIPOCYTE-TRANSCRIPTION FACTOR FREAC-11 (S12)

Template:ABSTRACT PUBMED 10669593

About this Structure

1D5V is a Single protein structure of sequence from Homo sapiens. Full experimental information is available from OCA.

Reference

Solution structure and dynamics of the DNA-binding domain of the adipocyte-transcription factor FREAC-11., van Dongen MJ, Cederberg A, Carlsson P, Enerback S, Wikstrom M, J Mol Biol. 2000 Feb 18;296(2):351-9. PMID:10669593

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