1day

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1day.jpg|left|200px]]
+
{{Seed}}
 +
[[Image:1day.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1day| PDB=1day | SCENE= }}
{{STRUCTURE_1day| PDB=1day | SCENE= }}
-
'''CRYSTAL STRUCTURE OF A BINARY COMPLEX OF PROTEIN KINASE CK2 (ALPHA-SUBUNIT) AND MG-GMPPNP'''
+
===CRYSTAL STRUCTURE OF A BINARY COMPLEX OF PROTEIN KINASE CK2 (ALPHA-SUBUNIT) AND MG-GMPPNP===
-
==Overview==
+
<!--
-
The structures of the catalytic subunit of protein kinase CK2 from Zea mays complexed with Mg2+ and with analogs of ATP or GTP were determined to 2.2 A resolution. Unlike most other protein kinases, CK2 from various sources shows 'dual-cosubstrate specificity', that is, the ability to efficiently use either ATP or GTP as a cosubstrate. The structures of these complexes demonstrate that water molecules are critical to switch the active site of CK2 from an ATP- to a GTP-compatible state. An understanding of the structural basis of dual-cosubstrate specificity may help in the design of drugs that target CK2 or other kinases with this property.
+
The line below this paragraph, {{ABSTRACT_PUBMED_10581548}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 10581548 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_10581548}}
==About this Structure==
==About this Structure==
Line 31: Line 35:
[[Category: Dual-cosubstrate specificity]]
[[Category: Dual-cosubstrate specificity]]
[[Category: Protein kinase ck2]]
[[Category: Protein kinase ck2]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 13:38:37 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 22:45:43 2008''

Revision as of 19:45, 30 June 2008

Image:1day.png

Template:STRUCTURE 1day

CRYSTAL STRUCTURE OF A BINARY COMPLEX OF PROTEIN KINASE CK2 (ALPHA-SUBUNIT) AND MG-GMPPNP

Template:ABSTRACT PUBMED 10581548

About this Structure

1DAY is a Single protein structure of sequence from Zea mays. Full crystallographic information is available from OCA.

Reference

GTP plus water mimic ATP in the active site of protein kinase CK2., Niefind K, Putter M, Guerra B, Issinger OG, Schomburg D, Nat Struct Biol. 1999 Dec;6(12):1100-3. PMID:10581548

Page seeded by OCA on Mon Jun 30 22:45:43 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1day"
Personal tools