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1dc0

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{{Seed}}
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{{STRUCTURE_1dc0| PDB=1dc0 | SCENE= }}
{{STRUCTURE_1dc0| PDB=1dc0 | SCENE= }}
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'''CRYSTAL STRUCTURE OF AN A/B-DNA INTERMEDIATE CATGGGCCCATG'''
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===CRYSTAL STRUCTURE OF AN A/B-DNA INTERMEDIATE CATGGGCCCATG===
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==Overview==
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The DNA dodecamer CATGGGCCCATG in a crystal structure of resolution 1.3 A has a conformation intermediate between A and B DNA. This trapping of a stable intermediate suggests that the A and B DNA families are not discrete, as previously believed. The structure supports a base-centered rather than a backbone-centered mechanism for the A &lt;--&gt; B transition mediated by guanine tracts. Interconversion between A and B DNA provides another means for regulating protein-DNA recognition.
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(as it appears on PubMed at http://www.pubmed.gov), where 10688897 is the PubMed ID number.
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{{ABSTRACT_PUBMED_10688897}}
==About this Structure==
==About this Structure==
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[[Category: B-dna]]
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[[Category: Intermediate]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 13:40:25 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 22:48:01 2008''

Revision as of 19:48, 30 June 2008

Image:1dc0.png

Template:STRUCTURE 1dc0

CRYSTAL STRUCTURE OF AN A/B-DNA INTERMEDIATE CATGGGCCCATG

Template:ABSTRACT PUBMED 10688897

About this Structure

Full crystallographic information is available from OCA.

Reference

The structure of a stable intermediate in the A <--> B DNA helix transition., Ng HL, Kopka ML, Dickerson RE, Proc Natl Acad Sci U S A. 2000 Feb 29;97(5):2035-9. PMID:10688897

Page seeded by OCA on Mon Jun 30 22:48:01 2008

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