1dnm

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{{STRUCTURE_1dnm| PDB=1dnm | SCENE= }}
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'''CRYSTAL STRUCTURE AND SEQUENCE-DEPENDENT CONFORMATION OF THE A.G MIS-PAIRED OLIGONUCLEOTIDE D(CGCAAGCTGGCG)'''
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===CRYSTAL STRUCTURE AND SEQUENCE-DEPENDENT CONFORMATION OF THE A.G MIS-PAIRED OLIGONUCLEOTIDE D(CGCAAGCTGGCG)===
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==Overview==
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The crystal structure of the dodecanucleotide d(CGCAAGCTGGCG) has been determined to a resolution of 2.5 A and refined to an R factor of 19.3% for 1710 reflections. The sequence crystallizes as a B-type double helix, with two G(anti).A(syn) base pairs. These are stabilized by three-center hydrogen bonds to pyrimidines that induce perturbations in base-pair geometry. The central AGCT region of the helix has a wide (greater than 6 A) minor groove.
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(as it appears on PubMed at http://www.pubmed.gov), where 2395870 is the PubMed ID number.
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{{ABSTRACT_PUBMED_2395870}}
==About this Structure==
==About this Structure==
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[[Category: Double helix]]
[[Category: Double helix]]
[[Category: Mismatched]]
[[Category: Mismatched]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 14:03:21 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 23:20:29 2008''

Revision as of 20:20, 30 June 2008

Image:1dnm.png

Template:STRUCTURE 1dnm

CRYSTAL STRUCTURE AND SEQUENCE-DEPENDENT CONFORMATION OF THE A.G MIS-PAIRED OLIGONUCLEOTIDE D(CGCAAGCTGGCG)

Template:ABSTRACT PUBMED 2395870

About this Structure

Full crystallographic information is available from OCA.

Reference

Crystal structure and sequence-dependent conformation of the A.G mispaired oligonucleotide d(CGCAAGCTGGCG)., Webster GD, Sanderson MR, Skelly JV, Neidle S, Swann PF, Li BF, Tickle IJ, Proc Natl Acad Sci U S A. 1990 Sep;87(17):6693-7. PMID:2395870

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