1dpn

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[[Image:1dpn.gif|left|200px]]
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{{Seed}}
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{{STRUCTURE_1dpn| PDB=1dpn | SCENE= }}
{{STRUCTURE_1dpn| PDB=1dpn | SCENE= }}
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'''B-DODECAMER CGCGAA(TAF)TCGCG WITH INCORPORATED 2'-DEOXY-2'-FLUORO-ARABINO-FURANOSYL THYMINE'''
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===B-DODECAMER CGCGAA(TAF)TCGCG WITH INCORPORATED 2'-DEOXY-2'-FLUORO-ARABINO-FURANOSYL THYMINE===
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==Overview==
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We have determined single crystal structures of an A-DNA decamer and a B-DNA dodecamer at 0.83 and 0.95 A, respectively. The resolution of the former is the highest reported thus far for any right-handed nucleic acid duplex and the quality of the diffraction data allowed determination of the structure with direct methods. The structures reveal unprecedented details of DNA fine structure and hydration; in particular, we have reexamined the overall hydration of A- and B-form DNA, the distribution of water around phosphate groups, and features of the water structure that may underlie the B to A transition.
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The line below this paragraph, {{ABSTRACT_PUBMED_10699842}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 10699842 is the PubMed ID number.
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{{ABSTRACT_PUBMED_10699842}}
==About this Structure==
==About this Structure==
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[[Category: Weeks, C M.]]
[[Category: Weeks, C M.]]
[[Category: 0 95 a resolution structure]]
[[Category: 0 95 a resolution structure]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 14:07:26 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 23:25:42 2008''

Revision as of 20:25, 30 June 2008

Image:1dpn.png

Template:STRUCTURE 1dpn

B-DODECAMER CGCGAA(TAF)TCGCG WITH INCORPORATED 2'-DEOXY-2'-FLUORO-ARABINO-FURANOSYL THYMINE

Template:ABSTRACT PUBMED 10699842

About this Structure

Full crystallographic information is available from OCA.

Reference

X-ray crystallographic analysis of the hydration of A- and B-form DNA at atomic resolution., Egli M, Tereshko V, Teplova M, Minasov G, Joachimiak A, Sanishvili R, Weeks CM, Miller R, Maier MA, An H, Dan Cook P, Manoharan M, Biopolymers. 1998;48(4):234-52. PMID:10699842

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