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1dpo

From Proteopedia

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[[Image:1dpo.gif|left|200px]]
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{{STRUCTURE_1dpo| PDB=1dpo | SCENE= }}
{{STRUCTURE_1dpo| PDB=1dpo | SCENE= }}
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'''STRUCTURE OF RAT TRYPSIN'''
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===STRUCTURE OF RAT TRYPSIN===
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==Overview==
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The structure of a rat trypsin mutant [S195C] at a temperature of 120 K has been refined to a crystallographic R factor of 17.4% between 12.0 and 1.59 A and is compared with the structure of the D102N mutant at 295 K. A reduction in the unit cell dimensions in going from room temperature to low temperature is accompanied by a decrease in molecular surface area and radius of gyration. The overall structure remains similar to that at room temperature. The attainable resolution appears to be improved due to the decrease in the fall off of intensities with resolution [reduction of the temperature factor]. This decreases the uncertainty in the atomic positions and allows the localization of more protein atoms and solvent molecules in the low temperature map. The largest differences between the two models occur at residues with higher than average temperature factors. Several features can be localized in the solvent region of the 120 K map that are not seen in the 295 K map. These include several more water molecules as well as an interstitial sulfate ion and two interstitial benzamidine molecules.
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The line below this paragraph, {{ABSTRACT_PUBMED_1881877}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 1881877 is the PubMed ID number.
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{{ABSTRACT_PUBMED_1881877}}
==About this Structure==
==About this Structure==
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[[Category: Signal]]
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[[Category: Zymogen]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 14:07:34 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 23:25:48 2008''

Revision as of 20:25, 30 June 2008

Image:1dpo.png

Template:STRUCTURE 1dpo

STRUCTURE OF RAT TRYPSIN

Template:ABSTRACT PUBMED 1881877

About this Structure

1DPO is a Single protein structure of sequence from Rattus rattus. Full crystallographic information is available from OCA.

Reference

1.59 A structure of trypsin at 120 K: comparison of low temperature and room temperature structures., Earnest T, Fauman E, Craik CS, Stroud R, Proteins. 1991;10(3):171-87. PMID:1881877

Page seeded by OCA on Mon Jun 30 23:25:48 2008

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