1dqc

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[[Image:1dqc.gif|left|200px]]
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{{STRUCTURE_1dqc| PDB=1dqc | SCENE= }}
{{STRUCTURE_1dqc| PDB=1dqc | SCENE= }}
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'''SOLUTION STRUCTURE OF TACHYCITIN, AN ANTIMICROBIAL PROTEIN WITH CHITIN-BINDING FUNCTION'''
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===SOLUTION STRUCTURE OF TACHYCITIN, AN ANTIMICROBIAL PROTEIN WITH CHITIN-BINDING FUNCTION===
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==Overview==
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Tachycitin, a 73-residue polypeptide having antimicrobial activity is present in the hemocyte of horseshoe crab (Tachypleus tridentatus). The first three-dimensional structure of invertebrate chitin-binding protein was determined for tachycitin using two-dimensional nuclear magnetic resonance spectroscopy. The measurements indicate that the structure of tachycitin is largely divided into N- and C-terminal domains; the former comprises a three-stranded beta-sheet and the latter a two-stranded beta-sheet following a short helical turn. The latter structural motif shares a significant tertiary structural similarity with the chitin-binding domain of plant chitin-binding protein. This result is thought to provide faithful experimental evidence to the recent hypothesis that chitin-binding proteins of invertebrates and plants are correlated by a convergent evolution process.
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(as it appears on PubMed at http://www.pubmed.gov), where 10770921 is the PubMed ID number.
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{{ABSTRACT_PUBMED_10770921}}
==About this Structure==
==About this Structure==
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1DQC is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Tachypleus_tridentatus Tachypleus tridentatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DQC OCA].
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1DQC is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Tachypleus_tridentatus Tachypleus tridentatus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DQC OCA].
==Reference==
==Reference==
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[[Category: Tsuda, S.]]
[[Category: Tsuda, S.]]
[[Category: Disulfide-rich]]
[[Category: Disulfide-rich]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 23:27:32 2008''

Revision as of 20:27, 30 June 2008

Image:1dqc.png

Template:STRUCTURE 1dqc

SOLUTION STRUCTURE OF TACHYCITIN, AN ANTIMICROBIAL PROTEIN WITH CHITIN-BINDING FUNCTION

Template:ABSTRACT PUBMED 10770921

About this Structure

1DQC is a Single protein structure of sequence from Tachypleus tridentatus. Full experimental information is available from OCA.

Reference

Chitin-binding proteins in invertebrates and plants comprise a common chitin-binding structural motif., Suetake T, Tsuda S, Kawabata S, Miura K, Iwanaga S, Hikichi K, Nitta K, Kawano K, J Biol Chem. 2000 Jun 16;275(24):17929-32. PMID:10770921

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