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1ds9

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[[Image:1ds9.jpg|left|200px]]
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{{STRUCTURE_1ds9| PDB=1ds9 | SCENE= }}
{{STRUCTURE_1ds9| PDB=1ds9 | SCENE= }}
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'''SOLUTION STRUCTURE OF CHLAMYDOMONAS OUTER ARM DYNEIN LIGHT CHAIN 1'''
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===SOLUTION STRUCTURE OF CHLAMYDOMONAS OUTER ARM DYNEIN LIGHT CHAIN 1===
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==Overview==
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Dyneins are molecular motors that translocate towards the minus ends of microtubules. In Chlamydomonas flagellar outer arm dynein, light chain 1 (LC1) associates with the nucleotide binding region within the gamma heavy chain motor domain and consists of a central leucine-rich repeat section that folds as a cylindrical right handed spiral formed from six beta-beta-alpha motifs. This central cylinder is flanked by terminal helical subdomains. The C-terminal helical domain juts out from the cylinder and is adjacent to a hydrophobic surface within the repeat region that is proposed to interact with the dynein heavy chain. The position of the C-terminal domain on LC1 and the unexpected structural similarity between LC1 and U2A' from the human spliceosome suggest that this domain interacts with the dynein motor domain.
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(as it appears on PubMed at http://www.pubmed.gov), where 10876244 is the PubMed ID number.
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{{ABSTRACT_PUBMED_10876244}}
==About this Structure==
==About this Structure==
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1DS9 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Chlamydomonas_reinhardtii Chlamydomonas reinhardtii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DS9 OCA].
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1DS9 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Chlamydomonas_reinhardtii Chlamydomonas reinhardtii]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DS9 OCA].
==Reference==
==Reference==
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[[Category: Flagella]]
[[Category: Flagella]]
[[Category: Leucine-rich repeat]]
[[Category: Leucine-rich repeat]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 14:12:48 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 23:32:20 2008''

Revision as of 20:32, 30 June 2008

Image:1ds9.png

Template:STRUCTURE 1ds9

SOLUTION STRUCTURE OF CHLAMYDOMONAS OUTER ARM DYNEIN LIGHT CHAIN 1

Template:ABSTRACT PUBMED 10876244

About this Structure

1DS9 is a Single protein structure of sequence from Chlamydomonas reinhardtii. Full experimental information is available from OCA.

Reference

Solution structure of a dynein motor domain associated light chain., Wu H, Maciejewski MW, Marintchev A, Benashski SE, Mullen GP, King SM, Nat Struct Biol. 2000 Jul;7(7):575-9. PMID:10876244

Page seeded by OCA on Mon Jun 30 23:32:20 2008

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