1dyl

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[[Image:1dyl.gif|left|200px]]
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{{Seed}}
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[[Image:1dyl.png|left|200px]]
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{{STRUCTURE_1dyl| PDB=1dyl | SCENE= }}
{{STRUCTURE_1dyl| PDB=1dyl | SCENE= }}
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'''9 ANGSTROM RESOLUTION CRYO-EM RECONSTRUCTION STRUCTURE OF SEMLIKI FOREST VIRUS (SFV) AND FITTING OF THE CAPSID PROTEIN STRUCTURE IN THE EM DENSITY'''
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===9 ANGSTROM RESOLUTION CRYO-EM RECONSTRUCTION STRUCTURE OF SEMLIKI FOREST VIRUS (SFV) AND FITTING OF THE CAPSID PROTEIN STRUCTURE IN THE EM DENSITY===
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==Overview==
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Semliki Forest virus serves as a paradigm for membrane fusion and assembly. Our icosahedral reconstruction combined 5276 particle images from 48 cryo-electron micrographs and determined the virion structure to 9 A resolution. The improved resolution of this map reveals an N-terminal arm linking capsid subunits and defines the spike-capsid interaction sites. It illustrates the paired helical nature of the transmembrane segments and the elongated structures connecting them to the spike projecting domains. A 10 A diameter density in the fusion protein lines the cavity at the center of the spike. These clearly visible features combine with the variation in order between the layers to provide a framework for understanding the structural changes during the life cycle of an enveloped virus.
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The line below this paragraph, {{ABSTRACT_PUBMED_10882067}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 10882067 is the PubMed ID number.
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{{ABSTRACT_PUBMED_10882067}}
==About this Structure==
==About this Structure==
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[[Category: Image reconstruction]]
[[Category: Image reconstruction]]
[[Category: Sfv]]
[[Category: Sfv]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 14:26:22 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 23:48:53 2008''

Revision as of 20:49, 30 June 2008

Template:STRUCTURE 1dyl

9 ANGSTROM RESOLUTION CRYO-EM RECONSTRUCTION STRUCTURE OF SEMLIKI FOREST VIRUS (SFV) AND FITTING OF THE CAPSID PROTEIN STRUCTURE IN THE EM DENSITY

Template:ABSTRACT PUBMED 10882067

About this Structure

1DYL is a Single protein structure of sequence from Semliki forest virus. Full crystallographic information is available from OCA.

Reference

Cryo-electron microscopy reveals the functional organization of an enveloped virus, Semliki Forest virus., Mancini EJ, Clarke M, Gowen BE, Rutten T, Fuller SD, Mol Cell. 2000 Feb;5(2):255-66. PMID:10882067

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