1f8v
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(New page: 200px<br /><applet load="1f8v" size="450" color="white" frame="true" align="right" spinBox="true" caption="1f8v, resolution 3.00Å" /> '''THE STRUCTURE OF PAR...)
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Revision as of 12:35, 20 November 2007
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THE STRUCTURE OF PARIACOTO VIRUS REVEALS A DODECAHEDRAL CAGE OF DUPLEX RNA
Overview
The 3.0 A resolution crystal structure of Pariacoto virus (PaV) reveals, extensive interactions between portions of the viral RNA genome and the, icosahedral capsid. Under the protein shell of the T = 3 quasi equivalent, capsid lies a dodecahedral cage composed of RNA duplex that accounts for, approximately 35% of the single-stranded RNA genome. The highly basic, N-terminal regions (residues 7-54) of the subunits, forming pentamers (A, subunits) are clearly visible in the density map and make numerous, interactions with the RNA cage. The C-terminal segments (residues 394-401), of the A subunits lie in channels near the quasi three-fold axes. Electron, cryo-microscopy and image reconstruction of PaV particles clearly show the, dodecahedral RNA cage.
About this Structure
1F8V is a Protein complex structure of sequences from Pariacato virus with SO4 and CA as ligands. Full crystallographic information is available from OCA.
Reference
The structure of pariacoto virus reveals a dodecahedral cage of duplex RNA., Tang L, Johnson KN, Ball LA, Lin T, Yeager M, Johnson JE, Nat Struct Biol. 2001 Jan;8(1):77-83. PMID:11135676
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