1flm
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(New page: 200px<br /><applet load="1flm" size="450" color="white" frame="true" align="right" spinBox="true" caption="1flm, resolution 1.30Å" /> '''DIMER OF FMN-BINDING...)
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Revision as of 12:54, 20 November 2007
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DIMER OF FMN-BINDING PROTEIN FROM DESULFOVIBRIO VULGARIS (MIYAZAKI F)
Overview
The crystal structure of FMN-binding protein (FMN-bp) from Desulfovibrio, vulgaris Miyazaki F was solved by the multiple isomorphous replacement, method and refined to an R factor of 15.1% at 1.3 A resolution. FMN-bp, exists in a dimeric form in the crystal, in contrast to the monomeric, structure determined by NMR. R.m.s. deviations between the crystal, structure and the solution structure are more than 2 A, which implies, significant differences. There are some hydrophobic residues in the, interface between the two monomers. In particular, Leu122 in the, C-terminus has a close contact with the o-xylene moiety of FMN, while, solvent molecules may cover the o-xylene moiety in the solution structure.
About this Structure
1FLM is a Single protein structure of sequence from Desulfovibrio vulgaris with FMN as ligand. Full crystallographic information is available from OCA.
Reference
How do the x-ray structure and the NMR structure of FMN-binding protein differ?, Suto K, Kawagoe K, Shibata N, Morimoto Y, Higuchi Y, Kitamura M, Nakaya T, Yasuoka N, Acta Crystallogr D Biol Crystallogr. 2000 Mar;56(Pt 3):368-71. PMID:10713530
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