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1fcs

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{{STRUCTURE_1fcs| PDB=1fcs | SCENE= }}
{{STRUCTURE_1fcs| PDB=1fcs | SCENE= }}
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'''CRYSTAL STRUCTURE OF A DISTAL SITE DOUBLE MUTANT OF SPERM WHALE MYOGLOBIN AT 1.6 ANGSTROMS RESOLUTION'''
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===CRYSTAL STRUCTURE OF A DISTAL SITE DOUBLE MUTANT OF SPERM WHALE MYOGLOBIN AT 1.6 ANGSTROMS RESOLUTION===
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==Overview==
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The three-dimensional structure of sperm whale myoglobin His64(E7)--&gt;Val,Thr67(E10)--&gt;Arg double mutant has been studied by X-ray crystallography at 1.6 A resolution, and refined to a crystallographic R-factor of 0.197. The Arg67(E10) side chain is extended in the direction of the ligand binding site, and its NH1 atom is at a distance of 3.11 A from the NH1 atom of Arg45(CD3), which is also pointing towards the distal site. Both are kept in this position by hydrogen bonding and electrostatic interactions with a solvent sulfate ion, located amongst the two, on the protein surface. No liganded water molecule is present at the sixth coordination position of the Fe(III) heme.
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The line below this paragraph, {{ABSTRACT_PUBMED_8462669}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 8462669 is the PubMed ID number.
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{{ABSTRACT_PUBMED_8462669}}
==About this Structure==
==About this Structure==
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[[Category: Rizzi, M.]]
[[Category: Rizzi, M.]]
[[Category: Oxygen transport]]
[[Category: Oxygen transport]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 16:10:54 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 03:03:28 2008''

Revision as of 00:03, 1 July 2008

Image:1fcs.png

Template:STRUCTURE 1fcs

CRYSTAL STRUCTURE OF A DISTAL SITE DOUBLE MUTANT OF SPERM WHALE MYOGLOBIN AT 1.6 ANGSTROMS RESOLUTION

Template:ABSTRACT PUBMED 8462669

About this Structure

1FCS is a Single protein structure of sequence from Physeter catodon. Full crystallographic information is available from OCA.

Reference

Crystal structure of a distal site double mutant of sperm whale myoglobin at 1.6 A resolution., Rizzi M, Bolognesi M, Coda A, Cutruzzola F, Allocatelli CT, Brancaccio A, Brunori M, FEBS Lett. 1993 Mar 29;320(1):13-6. PMID:8462669

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