1fcw

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[[Image:1fcw.gif|left|200px]]
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{{Seed}}
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[[Image:1fcw.png|left|200px]]
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{{STRUCTURE_1fcw| PDB=1fcw | SCENE= }}
{{STRUCTURE_1fcw| PDB=1fcw | SCENE= }}
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'''TRNA POSITIONS DURING THE ELONGATION CYCLE'''
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===TRNA POSITIONS DURING THE ELONGATION CYCLE===
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==Overview==
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Three-dimensional cryomaps have been reconstructed for tRNA-ribosome complexes in pre- and posttranslocational states at 17-A resolution. The positions of tRNAs in the A and P sites in the pretranslocational complexes and in the P and E sites in the posttranslocational complexes have been determined. Of these, the P-site tRNA position is the same as seen earlier in the initiation-like fMet-tRNA(f)(Met)-ribosome complex, where it was visualized with high accuracy. Now, the positions of the A- and E-site tRNAs are determined with similar accuracy. The positions of the CCA end of the tRNAs at the A site are different before and after peptide bond formation. The relative positions of anticodons of P- and E-site tRNAs in the posttranslocational state are such that a codon-anticodon interaction at the E site appears feasible.
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The line below this paragraph, {{ABSTRACT_PUBMED_10931859}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 10931859 is the PubMed ID number.
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{{ABSTRACT_PUBMED_10931859}}
==About this Structure==
==About this Structure==
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[[Category: Ribosome]]
[[Category: Ribosome]]
[[Category: Trna binding site]]
[[Category: Trna binding site]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 16:11:10 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 03:03:50 2008''

Revision as of 00:03, 1 July 2008

Image:1fcw.png

Template:STRUCTURE 1fcw

TRNA POSITIONS DURING THE ELONGATION CYCLE

Template:ABSTRACT PUBMED 10931859

About this Structure

Full crystallographic information is available from OCA.

Reference

Visualization of tRNA movements on the Escherichia coli 70S ribosome during the elongation cycle., Agrawal RK, Spahn CM, Penczek P, Grassucci RA, Nierhaus KH, Frank J, J Cell Biol. 2000 Aug 7;150(3):447-60. PMID:10931859

Page seeded by OCA on Tue Jul 1 03:03:50 2008

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