1fml

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[[Image:1fml.gif|left|200px]]
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{{Seed}}
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[[Image:1fml.png|left|200px]]
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{{STRUCTURE_1fml| PDB=1fml | SCENE= }}
{{STRUCTURE_1fml| PDB=1fml | SCENE= }}
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'''CRYSTAL STRUCTURE OF RETINOL DEHYDRATASE IN A COMPLEX WITH RETINOL AND PAP'''
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===CRYSTAL STRUCTURE OF RETINOL DEHYDRATASE IN A COMPLEX WITH RETINOL AND PAP===
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==Overview==
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We report here the crystal structure of retinol dehydratase, an enzyme that catalyzes the synthesis of anhydroretinol. The enzyme is a member of the sulfotransferase superfamily and its crystal structure reveals the insertion of a helical lid into a canonical sulfotransferase fold. Site-directed mutations demonstrate that this inserted lid is necessary for anhydroretinol production but not for sulfonation; thus, insertion of a helical lid can convert a sulfotransferase into a dehydratase.
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(as it appears on PubMed at http://www.pubmed.gov), where 11323722 is the PubMed ID number.
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{{ABSTRACT_PUBMED_11323722}}
==About this Structure==
==About this Structure==
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[[Category: Retinol]]
[[Category: Retinol]]
[[Category: Sulfotransferase]]
[[Category: Sulfotransferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 16:30:32 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 03:29:44 2008''

Revision as of 00:29, 1 July 2008

Image:1fml.png

Template:STRUCTURE 1fml

CRYSTAL STRUCTURE OF RETINOL DEHYDRATASE IN A COMPLEX WITH RETINOL AND PAP

Template:ABSTRACT PUBMED 11323722

About this Structure

1FML is a Single protein structure of sequence from Spodoptera frugiperda. Full crystallographic information is available from OCA.

Reference

A helical lid converts a sulfotransferase to a dehydratase., Pakhomova S, Kobayashi M, Buck J, Newcomer ME, Nat Struct Biol. 2001 May;8(5):447-51. PMID:11323722

Page seeded by OCA on Tue Jul 1 03:29:44 2008

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