1fs0

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[[Image:1fs0.jpg|left|200px]]
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{{Seed}}
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[[Image:1fs0.png|left|200px]]
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{{STRUCTURE_1fs0| PDB=1fs0 | SCENE= }}
{{STRUCTURE_1fs0| PDB=1fs0 | SCENE= }}
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'''COMPLEX OF GAMMA/EPSILON ATP SYNTHASE FROM E.COLI'''
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===COMPLEX OF GAMMA/EPSILON ATP SYNTHASE FROM E.COLI===
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==Overview==
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ATP synthases (F(1)F(o)-ATPases) use energy released by the movement of protons down a transmembrane electrochemical gradient to drive the synthesis of ATP, the universal biological energy currency. Proton flow through F(o) drives rotation of a ring of c-subunits and a complex of the gamma and epsilon-subunits, causing cyclical conformational changes in F(1) that are required for catalysis. The crystal structure of a large portion of F(1) has been resolved. However, the structure of the central portion of the enzyme, through which conformational changes in F(o) are communicated to F(1), has until now remained elusive. Here we report the crystal structure of a complex of the epsilon-subunit and the central domain of the gamma-subunit refined at 2.1 A resolution. The structure reveals how rotation of these subunits causes large conformational changes in F(1), and thereby provides new insights into energy coupling between F(o) and F(1).
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The line below this paragraph, {{ABSTRACT_PUBMED_11062562}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 11062562 is the PubMed ID number.
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{{ABSTRACT_PUBMED_11062562}}
==About this Structure==
==About this Structure==
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[[Category: Epsilon]]
[[Category: Epsilon]]
[[Category: Gamma]]
[[Category: Gamma]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 16:41:47 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 03:51:26 2008''

Revision as of 00:51, 1 July 2008

Image:1fs0.png

Template:STRUCTURE 1fs0

COMPLEX OF GAMMA/EPSILON ATP SYNTHASE FROM E.COLI

Template:ABSTRACT PUBMED 11062562

About this Structure

1FS0 is a Protein complex structure of sequences from Escherichia coli. Full crystallographic information is available from OCA.

Reference

Structure of the gamma-epsilon complex of ATP synthase., Rodgers AJ, Wilce MC, Nat Struct Biol. 2000 Nov;7(11):1051-4. PMID:11062562

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