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1frv
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(New page: 200px<br /><applet load="1frv" size="450" color="white" frame="true" align="right" spinBox="true" caption="1frv, resolution 2.85Å" /> '''CRYSTAL STRUCTURE OF...)
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Revision as of 13:05, 20 November 2007
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CRYSTAL STRUCTURE OF THE OXIDIZED FORM OF NI-FE HYDROGENASE
Overview
The X-ray structure of the heterodimeric Ni-Fe hydrogenase from, Desulfovibrio gigas, the enzyme responsible for the metabolism of, molecular hydrogen, has been solved at 2.85 A resolution. The active site, which appears to contain, besides nickel, a second metal ion, is buried in, the 60K subunit. The 28K subunit, which coordinates one [3Fe-4S] and two, [4Fe-4S] clusters, contains an amino-terminal domain with similarities to, the redox protein flavodoxin. The structure suggests plausible electron, and proton transfer pathways.
About this Structure
1FRV is a Protein complex structure of sequences from Desulfovibrio gigas with NI, SF4, F3S and FEL as ligands. Active as Cytochrome-c3 hydrogenase, with EC number 1.12.2.1 Full crystallographic information is available from OCA.
Reference
Crystal structure of the nickel-iron hydrogenase from Desulfovibrio gigas., Volbeda A, Charon MH, Piras C, Hatchikian EC, Frey M, Fontecilla-Camps JC, Nature. 1995 Feb 16;373(6515):580-7. PMID:7854413
Page seeded by OCA on Tue Nov 20 15:12:38 2007
