1go5

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1go5.jpg|left|200px]]
+
{{Seed}}
 +
[[Image:1go5.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1go5| PDB=1go5 | SCENE= }}
{{STRUCTURE_1go5| PDB=1go5 | SCENE= }}
-
'''STRUCTURE OF THE C-TERMINAL FG-BINDING DOMAIN OF HUMAN TAP'''
+
===STRUCTURE OF THE C-TERMINAL FG-BINDING DOMAIN OF HUMAN TAP===
-
==Overview==
+
<!--
-
The vertebrate Tap protein is a member of the NXF family of shuttling transport receptors for nuclear export of mRNA. Tap has a modular structure, and its most C-terminal domain is important for binding to FG repeat-containing nuclear pore proteins (FG-nucleoporins) and is sufficient to mediate nuclear shuttling. We report the solution structure of this C-terminal domain, which is based on a distinctive arrangement of four alpha-helices and is joined to the next module by a flexible 12-residue Pro-rich linker. F617A Tap suppresses FG-nucleoporin binding by the most C-terminal domain that, together with the structure of the other modules from which Tap is constructed, provides a structural context for its nuclear shuttling function.
+
The line below this paragraph, {{ABSTRACT_PUBMED_11875519}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 11875519 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_11875519}}
==About this Structure==
==About this Structure==
-
1GO5 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GO5 OCA].
+
1GO5 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GO5 OCA].
==Reference==
==Reference==
Line 30: Line 34:
[[Category: Nucleoporin]]
[[Category: Nucleoporin]]
[[Category: Uba]]
[[Category: Uba]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 17:48:46 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 05:35:25 2008''

Revision as of 02:35, 1 July 2008

Image:1go5.png

Template:STRUCTURE 1go5

STRUCTURE OF THE C-TERMINAL FG-BINDING DOMAIN OF HUMAN TAP

Template:ABSTRACT PUBMED 11875519

About this Structure

1GO5 is a Single protein structure of sequence from Homo sapiens. Full experimental information is available from OCA.

Reference

Structure of the C-terminal FG-nucleoporin binding domain of Tap/NXF1., Grant RP, Hurt E, Neuhaus D, Stewart M, Nat Struct Biol. 2002 Apr;9(4):247-51. PMID:11875519

Page seeded by OCA on Tue Jul 1 05:35:25 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1go5"
Personal tools