This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
6rhn
From Proteopedia
OCA (Talk | contribs)
(New page: 200px<br /> <applet load="6rhn" size="450" color="white" frame="true" align="right" spinBox="true" caption="6rhn, resolution 2.15Å" /> '''HISTIDINE TRIAD NUC...)
Next diff →
Revision as of 17:46, 29 October 2007
|
HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN (HINT) FROM RABBIT WITHOUT NUCLEOTIDE
Overview
Histidine triad nucleotide-binding protein (HINT), a dimeric purine, nucleotide-binding protein from rabbit heart, is a member of the HIT, (histidine triad) superfamily which includes HINT homologues and FHIT (HIT, protein encoded at the chromosome 3 fragile site) homologues. Crystal, structures of HINT-nucleotide complexes demonstrate that the most, conserved residues in the superfamily mediate nucleotide binding and that, the HIT motif forms part of the phosphate binding loop., Galactose-1-phosphate uridylyltransferase, whose deficiency causes, galactosemia, contains tandem HINT domains with the same fold and mode of, nucleotide binding as HINT despite having no overall sequence similarity., Features of FHIT, a diadenosine polyphosphate hydrolase and candidate, tumour suppressor, are ... [(full description)]
About this Structure
6RHN is a [Single protein] structure of sequence from [Oryctolagus cuniculus]. Full crystallographic information is available from [OCA].
Reference
Crystal structures of HINT demonstrate that histidine triad proteins are GalT-related nucleotide-binding proteins., Brenner C, Garrison P, Gilmour J, Peisach D, Ringe D, Petsko GA, Lowenstein JM, Nat Struct Biol. 1997 Mar;4(3):231-8. PMID:9164465
Page seeded by OCA on Mon Oct 29 19:51:39 2007
