This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1h7v

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1h7v.jpg|left|200px]]
+
{{Seed}}
 +
[[Image:1h7v.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1h7v| PDB=1h7v | SCENE= }}
{{STRUCTURE_1h7v| PDB=1h7v | SCENE= }}
-
'''RUBREDOXIN FROM GUILLARDIA THETA'''
+
===RUBREDOXIN FROM GUILLARDIA THETA===
-
==Overview==
+
<!--
-
The rubredoxin from the cryptomonad Guillardia theta is one of the first examples of a rubredoxin encoded in a eukaryotic organism. The structure of a soluble zinc-substituted 70-residue G. theta rubredoxin lacking the membrane anchor and the thylakoid targeting sequence was determined by multidimensional heteronuclear NMR, representing the first three-dimensional (3D) structure of a eukaryotic rubredoxin. For the structure calculation a strategy was applied in which information about hydrogen bonds was directly inferred from a long-range HNCO experiment, and the dynamics of the protein was deduced from heteronuclear nuclear Overhauser effect data and exchange rates of the amide protons. The structure is well defined, exhibiting average root-mean-square deviations of 0.21 A for the backbone heavy atoms and 0.67 A for all heavy atoms of residues 7-56, and an increased flexibility toward the termini. The structure of this core fold is almost identical to that of prokaryotic rubredoxins. There are, however, significant differences with respect to the charge distribution at the protein surface, suggesting that G. theta rubredoxin exerts a different physiological function compared to the structurally characterized prokaryotic rubredoxins. The amino-terminal residues containing the putative signal peptidase recognition/cleavage site show an increased flexibility compared to the core fold, but still adopt a defined 3D orientation, which is mainly stabilized by nonlocal interactions to residues of the carboxy-terminal region. This orientation might reflect the structural elements and charge pattern necessary for correct signal peptidase recognition of the G. theta rubredoxin precursor.
+
The line below this paragraph, {{ABSTRACT_PUBMED_10975569}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 10975569 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_10975569}}
==About this Structure==
==About this Structure==
-
1H7V is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Guillardia_theta Guillardia theta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H7V OCA].
+
1H7V is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Guillardia_theta Guillardia theta]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H7V OCA].
==Reference==
==Reference==
Line 34: Line 38:
[[Category: Rubredoxin]]
[[Category: Rubredoxin]]
[[Category: Zinc-substitution]]
[[Category: Zinc-substitution]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 18:32:53 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 06:46:09 2008''

Revision as of 03:46, 1 July 2008

Image:1h7v.png

Template:STRUCTURE 1h7v

RUBREDOXIN FROM GUILLARDIA THETA

Template:ABSTRACT PUBMED 10975569

About this Structure

1H7V is a Single protein structure of sequence from Guillardia theta. Full experimental information is available from OCA.

Reference

Solution structure of a zinc substituted eukaryotic rubredoxin from the cryptomonad alga Guillardia theta., Schweimer K, Hoffmann S, Wastl J, Maier UG, Rosch P, Sticht H, Protein Sci. 2000 Aug;9(8):1474-86. PMID:10975569

Page seeded by OCA on Tue Jul 1 06:46:09 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1h7v"
Personal tools