1hi9

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{{STRUCTURE_1hi9| PDB=1hi9 | SCENE= }}
{{STRUCTURE_1hi9| PDB=1hi9 | SCENE= }}
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'''ZN-DEPENDENT D-AMINOPEPTIDASE DPPA FROM BACILLUS SUBTILIS, A SELF-COMPARTMENTALIZING PROTEASE.'''
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===ZN-DEPENDENT D-AMINOPEPTIDASE DPPA FROM BACILLUS SUBTILIS, A SELF-COMPARTMENTALIZING PROTEASE.===
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==Overview==
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Bacillus subtilis DppA is a binuclear zinc-dependent, D-specific aminopeptidase. The X-ray structure of the enzyme has been determined at 2.4 A resolution by a three-wavelength MAD experiment. The structure reveals that DppA is a new example of a 'self-compartmentalizing protease', a family of proteolytic complexes. Proteasomes are the most extensively studied representatives of this family. The DppA enzyme is composed of identical 30 kDa subunits organized in a decamer with 52 point-group symmetry. A 20 A wide channel runs through the complex, giving access to a central chamber holding the active sites. The structure shows DppA to be a prototype of a new family of metalloaminopeptidases characterized by the SXDXEG key sequence.
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The line below this paragraph, {{ABSTRACT_PUBMED_11473256}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 11473256 is the PubMed ID number.
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{{ABSTRACT_PUBMED_11473256}}
==About this Structure==
==About this Structure==
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[[Category: Protease]]
[[Category: Protease]]
[[Category: Self-compartmentalizing]]
[[Category: Self-compartmentalizing]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 18:52:22 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 08:13:22 2008''

Revision as of 05:13, 1 July 2008

Image:1hi9.png

Template:STRUCTURE 1hi9

ZN-DEPENDENT D-AMINOPEPTIDASE DPPA FROM BACILLUS SUBTILIS, A SELF-COMPARTMENTALIZING PROTEASE.

Template:ABSTRACT PUBMED 11473256

About this Structure

1HI9 is a Single protein structure of sequence from Bacillus subtilis. Full crystallographic information is available from OCA.

Reference

Structure of the Bacillus subtilis D-aminopeptidase DppA reveals a novel self-compartmentalizing protease., Remaut H, Bompard-Gilles C, Goffin C, Frere JM, Van Beeumen J, Nat Struct Biol. 2001 Aug;8(8):674-8. PMID:11473256

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