This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1hml

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1hml.gif|left|200px]]
+
{{Seed}}
 +
[[Image:1hml.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1hml| PDB=1hml | SCENE= }}
{{STRUCTURE_1hml| PDB=1hml | SCENE= }}
-
'''ALPHA_LACTALBUMIN POSSESSES A DISTINCT ZINC BINDING SITE'''
+
===ALPHA_LACTALBUMIN POSSESSES A DISTINCT ZINC BINDING SITE===
-
==Overview==
+
<!--
-
It has been proposed that the binding of Zn2+ to alpha-lactalbumin switches the conformation to one akin to a state intermediate in the folding of the protein. However, the high resolution x-ray crystal structure of human alpha-lactalbumin-Zn2+ complex at 1.7-A resolution (pH 7.6) does not reveal any significant change in conformation from the native state. The Zn2+ ion binds specifically in the "cleft" of alpha-lactalbumin (the region which forms the active site of the homologous protein lysozyme). This may suggest a possible role for Zn2+ binding in lactose synthase complex. The coordination of the Zn2+ ion involves a symmetry-related molecule in the crystal, the crystal contacts being stabilized by a SO4(2-) ion bound at the interface between three molecules.
+
The line below this paragraph, {{ABSTRACT_PUBMED_8366079}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 8366079 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_8366079}}
==About this Structure==
==About this Structure==
Line 27: Line 31:
[[Category: Stuart, D I.]]
[[Category: Stuart, D I.]]
[[Category: Calcium-binding protein]]
[[Category: Calcium-binding protein]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 19:01:06 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 08:24:19 2008''

Revision as of 05:24, 1 July 2008

Image:1hml.png

Template:STRUCTURE 1hml

ALPHA_LACTALBUMIN POSSESSES A DISTINCT ZINC BINDING SITE

Template:ABSTRACT PUBMED 8366079

About this Structure

1HML is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Alpha-lactalbumin possesses a distinct zinc binding site., Ren J, Stuart DI, Acharya KR, J Biol Chem. 1993 Sep 15;268(26):19292-8. PMID:8366079

Page seeded by OCA on Tue Jul 1 08:24:19 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1hml"
Personal tools