1hmy

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{{STRUCTURE_1hmy| PDB=1hmy | SCENE= }}
{{STRUCTURE_1hmy| PDB=1hmy | SCENE= }}
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'''CRYSTAL STRUCTURE OF THE HHAL DNA METHYLTRANSFERASE COMPLEXED WITH S-ADENOSYL-L-METHIONINE'''
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===CRYSTAL STRUCTURE OF THE HHAL DNA METHYLTRANSFERASE COMPLEXED WITH S-ADENOSYL-L-METHIONINE===
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==Overview==
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The first three-dimensional structure of a DNA methyltransferase is presented. The crystal structure of the DNA (cytosine-5)-methyltransferase, M.HhaI (recognition sequence: GCGC), complexed with S-adenosyl-L-methionine has been determined and refined at 2.5 A resolution. The core of the structure is dominated by sequence motifs conserved among all DNA (cytosine-5)-methyltransferases, and these are responsible for cofactor binding and methyltransferase function.
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(as it appears on PubMed at http://www.pubmed.gov), where 8343957 is the PubMed ID number.
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{{ABSTRACT_PUBMED_8343957}}
==About this Structure==
==About this Structure==
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[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Cheng, X.]]
[[Category: Cheng, X.]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 19:01:36 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 08:24:57 2008''

Revision as of 05:24, 1 July 2008

Template:STRUCTURE 1hmy

CRYSTAL STRUCTURE OF THE HHAL DNA METHYLTRANSFERASE COMPLEXED WITH S-ADENOSYL-L-METHIONINE

Template:ABSTRACT PUBMED 8343957

About this Structure

1HMY is a Single protein structure of sequence from Haemophilus haemolyticus. Full crystallographic information is available from OCA.

Reference

Crystal structure of the HhaI DNA methyltransferase complexed with S-adenosyl-L-methionine., Cheng X, Kumar S, Posfai J, Pflugrath JW, Roberts RJ, Cell. 1993 Jul 30;74(2):299-307. PMID:8343957

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