This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1hrj

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1hrj.jpg|left|200px]]
+
{{Seed}}
 +
[[Image:1hrj.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1hrj| PDB=1hrj | SCENE= }}
{{STRUCTURE_1hrj| PDB=1hrj | SCENE= }}
-
'''HUMAN RANTES, NMR, 13 STRUCTURES'''
+
===HUMAN RANTES, NMR, 13 STRUCTURES===
-
==Overview==
+
<!--
-
The solution structure of the chemokine RANTES (regulated on activation, normal T-cell expressed and secreted) has been determined using NMR spectroscopy. Backbone and side-chain 1H and 15N assignments have been obtained using a combination of two-dimensional homonuclear and three-dimensional heteronuclear spectra. Regular elements of secondary structure have been identified on the basis of a qualitative interpretation of NOE data, J(NH-H alpha) coupling constants, and amide exchange rates. Three-dimensional structures were calculated from a total of 2146 experimental restraints using a combination of distance geometry and simulated annealing protocols. For the 13 best structures the average backbone (N, C alpha, C) atomic rmsd from the mean coordinates for residues 5-65 is 0.64 A (+/- 0.14 A) for the dimer and 0.50 A (+/- 0.08 A) for the individual monomers. Each monomer consists of a three-stranded antiparallel beta-sheet (residues 26-30, 38-43, 48-51) in a Greek key motif with a C-terminal helix (56-65) packed across the sheet, an arrangement similar to the monomeric structure of other members of this chemokine family (IL-8, PF4, MGSA/Gro alpha, and MIP-1 beta). Overall, the RANTES dimer resembles that previously reported for MIP-1 beta.
+
The line below this paragraph, {{ABSTRACT_PUBMED_7542919}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 7542919 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_7542919}}
==About this Structure==
==About this Structure==
-
1HRJ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HRJ OCA].
+
1HRJ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HRJ OCA].
==Reference==
==Reference==
Line 27: Line 31:
[[Category: Wells, T N.C.]]
[[Category: Wells, T N.C.]]
[[Category: Cc chemokine]]
[[Category: Cc chemokine]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 19:09:45 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 08:35:18 2008''

Revision as of 05:35, 1 July 2008

Image:1hrj.png

Template:STRUCTURE 1hrj

HUMAN RANTES, NMR, 13 STRUCTURES

Template:ABSTRACT PUBMED 7542919

About this Structure

1HRJ is a Single protein structure of sequence from Homo sapiens. Full experimental information is available from OCA.

Reference

The three-dimensional solution structure of RANTES., Chung CW, Cooke RM, Proudfoot AE, Wells TN, Biochemistry. 1995 Jul 25;34(29):9307-14. PMID:7542919

Page seeded by OCA on Tue Jul 1 08:35:18 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1hrj"
Personal tools