1hyn

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1hyn.gif|left|200px]]
+
{{Seed}}
 +
[[Image:1hyn.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1hyn| PDB=1hyn | SCENE= }}
{{STRUCTURE_1hyn| PDB=1hyn | SCENE= }}
-
'''CRYSTAL STRUCTURE OF THE CYTOPLASMIC DOMAIN OF HUMAN ERYTHROCYTE BAND-3 PROTEIN'''
+
===CRYSTAL STRUCTURE OF THE CYTOPLASMIC DOMAIN OF HUMAN ERYTHROCYTE BAND-3 PROTEIN===
-
==Overview==
+
<!--
-
The red blood cell membrane (RBCM) is a primary model for animal cell plasma membranes. One of its major organizing centers is the cytoplasmic domain of band 3 (cdb3), which links multiple proteins to the membrane. Included among its peripheral protein ligands are ankyrin (the major bridge to the spectrin-actin skeleton), protein 4. 1, protein 4.2, aldolase, glyceraldehyde-3-phosphate dehydrogenase, phosphofructokinase, deoxyhemoglobin, p72syk protein tyrosine kinase, and hemichromes. The crystal structure of cdb3 is reported at 0.26 nm (2.6 A) resolution. A tight symmetric dimer is formed by cdb3; it is stabilized by interlocked dimerization arms contributed by both monomers. Each subunit also includes a larger peripheral protein binding domain with an alpha(+) beta-fold. The binding sites of several peripheral proteins are localized in the structure, and the nature of the major conformational change that regulates membrane-skeletal interactions is evaluated. An improved structural definition of the protein network at the inner surface of the RBCM is now possible.
+
The line below this paragraph, {{ABSTRACT_PUBMED_11049968}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 11049968 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_11049968}}
==About this Structure==
==About this Structure==
Line 27: Line 31:
[[Category: Zhang, D.]]
[[Category: Zhang, D.]]
[[Category: Membrane protein]]
[[Category: Membrane protein]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 19:22:02 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 10:08:18 2008''

Revision as of 07:08, 1 July 2008

Image:1hyn.png

Template:STRUCTURE 1hyn

CRYSTAL STRUCTURE OF THE CYTOPLASMIC DOMAIN OF HUMAN ERYTHROCYTE BAND-3 PROTEIN

Template:ABSTRACT PUBMED 11049968

About this Structure

1HYN is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Crystallographic structure and functional interpretation of the cytoplasmic domain of erythrocyte membrane band 3., Zhang D, Kiyatkin A, Bolin JT, Low PS, Blood. 2000 Nov 1;96(9):2925-33. PMID:11049968

Page seeded by OCA on Tue Jul 1 10:08:18 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1hyn"
Personal tools