1hyw

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[[Image:1hyw.gif|left|200px]]
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{{STRUCTURE_1hyw| PDB=1hyw | SCENE= }}
{{STRUCTURE_1hyw| PDB=1hyw | SCENE= }}
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'''SOLUTION STRUCTURE OF BACTERIOPHAGE LAMBDA GPW'''
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===SOLUTION STRUCTURE OF BACTERIOPHAGE LAMBDA GPW===
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==Overview==
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Protein W (gpW) from bacteriophage lambda is required for the stabilization of DNA within the phage head and for attachment of tails onto the head during morphogenesis. Although comprised of only 68 residues, it likely interacts with at least two other proteins in the mature phage and with DNA. Thus, gpW is an intriguing subject for detailed structural studies. We have determined its solution structure using NMR spectroscopy and have found it to possesses a novel fold consisting of two alpha-helices and a single two-stranded beta-sheet arranged around a well-packed hydrophobic core. The 14 C-terminal residues of gpW, which are essential for function, are unstructured in solution.
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(as it appears on PubMed at http://www.pubmed.gov), where 11302702 is the PubMed ID number.
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{{ABSTRACT_PUBMED_11302702}}
==About this Structure==
==About this Structure==
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1HYW is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_lambda Enterobacteria phage lambda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HYW OCA].
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1HYW is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_lambda Enterobacteria phage lambda]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HYW OCA].
==Reference==
==Reference==
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[[Category: One two-stranded beta-sheet]]
[[Category: One two-stranded beta-sheet]]
[[Category: Two helice]]
[[Category: Two helice]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 19:22:36 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 10:09:09 2008''

Revision as of 07:09, 1 July 2008

Image:1hyw.png

Template:STRUCTURE 1hyw

SOLUTION STRUCTURE OF BACTERIOPHAGE LAMBDA GPW

Template:ABSTRACT PUBMED 11302702

About this Structure

1HYW is a Single protein structure of sequence from Enterobacteria phage lambda. Full experimental information is available from OCA.

Reference

The solution structure of bacteriophage lambda protein W, a small morphogenetic protein possessing a novel fold., Maxwell KL, Yee AA, Booth V, Arrowsmith CH, Gold M, Davidson AR, J Mol Biol. 2001 Apr 20;308(1):9-14. PMID:11302702

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