This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1idz

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1idz.jpg|left|200px]]
+
{{Seed}}
 +
[[Image:1idz.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1idz| PDB=1idz | SCENE= }}
{{STRUCTURE_1idz| PDB=1idz | SCENE= }}
-
'''STRUCTURE OF MYB TRANSFORMING PROTEIN, NMR, 20 STRUCTURES'''
+
===STRUCTURE OF MYB TRANSFORMING PROTEIN, NMR, 20 STRUCTURES===
-
==Overview==
+
<!--
-
A small globular protein, the third repeat of the c-Myb DNA-binding domain, which is composed of 54 amino acid residues, was engineered so as to understand the structural uniqueness of native proteins. This small protein has three alpha-helices that form a helix-turn-helix structure, which is maintained by the hydrophobic core with three Ile residues. One of the mutant proteins, with two of the buried Ile (Ile-155 and Ile-181) substituted with Leu residues, showed multiple conformations, as monitored by heteronuclear magnetic resonance spectroscopy for 13C- and 15N-labeled proteins. The increase in the side-chain conformational entropy, caused by changing the Ile to a Leu residue on an alpha-helix, could engender the lack of structural uniqueness. In native proteins, the conformations of not only the beta-branched side chains, but also those of the neighboring bulky side chains, can be greatly restricted, depending upon the local backbone structure.
+
The line below this paragraph, {{ABSTRACT_PUBMED_8942977}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 8942977 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_8942977}}
==About this Structure==
==About this Structure==
-
1IDZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IDZ OCA].
+
1IDZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IDZ OCA].
==Reference==
==Reference==
Line 27: Line 31:
[[Category: Dna-binding protein]]
[[Category: Dna-binding protein]]
[[Category: Protooncogene product]]
[[Category: Protooncogene product]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 19:53:40 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 10:49:28 2008''

Revision as of 07:49, 1 July 2008

Image:1idz.png

Template:STRUCTURE 1idz

STRUCTURE OF MYB TRANSFORMING PROTEIN, NMR, 20 STRUCTURES

Template:ABSTRACT PUBMED 8942977

About this Structure

1IDZ is a Single protein structure of sequence from Mus musculus. Full experimental information is available from OCA.

Reference

A small engineered protein lacks structural uniqueness by increasing the side-chain conformational entropy., Furukawa K, Oda M, Nakamura H, Proc Natl Acad Sci U S A. 1996 Nov 26;93(24):13583-8. PMID:8942977

Page seeded by OCA on Tue Jul 1 10:49:28 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1idz"
Personal tools