1ihv

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1ihv.gif|left|200px]]
+
{{Seed}}
 +
[[Image:1ihv.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1ihv| PDB=1ihv | SCENE= }}
{{STRUCTURE_1ihv| PDB=1ihv | SCENE= }}
-
'''SOLUTION STRUCTURE OF THE DNA BINDING DOMAIN OF HIV-1 INTEGRASE, NMR, MINIMIZED AVERAGE STRUCTURE'''
+
===SOLUTION STRUCTURE OF THE DNA BINDING DOMAIN OF HIV-1 INTEGRASE, NMR, MINIMIZED AVERAGE STRUCTURE===
-
==Overview==
+
<!--
-
The solution structure of the DNA binding domain of HIV-1 integrase (residues 220-270) has been determined by multidimensional NMR spectroscopy. The protein is a dimer in solution, and each subunit is composed of a five-stranded beta-barrel with a topology very similar to that of the SH3 domain. The dimer is formed by a stacked beta-interface comprising strands 2, 3, and 4, with the two triple-stranded antiparallel beta-sheets, one from each subunit, oriented antiparallel to each other. One surface of the dimer, bounded by the loop between strands beta 1 and beta 2, forms a saddle-shaped groove with dimensions of approximately 24 x 23 x 12 A in cross section. Lys264, which has been shown from mutational data to be involved in DNA binding, protrudes from this surface, implicating the saddle-shaped groove as the potential DNA binding site.
+
The line below this paragraph, {{ABSTRACT_PUBMED_7632683}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 7632683 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_7632683}}
==About this Structure==
==About this Structure==
-
1IHV is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus Human immunodeficiency virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IHV OCA].
+
1IHV is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus Human immunodeficiency virus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IHV OCA].
==Reference==
==Reference==
Line 29: Line 33:
[[Category: Dna-binding protein]]
[[Category: Dna-binding protein]]
[[Category: Polyprotein]]
[[Category: Polyprotein]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 20:01:13 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 12:13:40 2008''

Revision as of 09:13, 1 July 2008

Image:1ihv.png

Template:STRUCTURE 1ihv

SOLUTION STRUCTURE OF THE DNA BINDING DOMAIN OF HIV-1 INTEGRASE, NMR, MINIMIZED AVERAGE STRUCTURE

Template:ABSTRACT PUBMED 7632683

About this Structure

1IHV is a Single protein structure of sequence from Human immunodeficiency virus. Full experimental information is available from OCA.

Reference

Solution structure of the DNA binding domain of HIV-1 integrase., Lodi PJ, Ernst JA, Kuszewski J, Hickman AB, Engelman A, Craigie R, Clore GM, Gronenborn AM, Biochemistry. 1995 Aug 8;34(31):9826-33. PMID:7632683

Page seeded by OCA on Tue Jul 1 12:13:40 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1ihv"
Personal tools