1iug

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1iug.jpg|left|200px]]
+
{{Seed}}
 +
[[Image:1iug.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1iug| PDB=1iug | SCENE= }}
{{STRUCTURE_1iug| PDB=1iug | SCENE= }}
-
'''The crystal structure of aspartate aminotransferase which belongs to subgroup IV from Thermus thermophilus'''
+
===The crystal structure of aspartate aminotransferase which belongs to subgroup IV from Thermus thermophilus===
-
==Overview==
+
<!--
-
Protein TT0402 from Thermus thermophilus HB8 exhibits about 30-35% sequence identity with proteins belonging to subgroup IV in the aminotransferase family of the fold-type I pyridoxal 5'-phosphate (PLP)-dependent enzymes. In this study, we determined the crystal structure of TT0402 at 2.3 A resolution (R(factor) = 19.9%, R(free) = 23.6%). The overall structure of TT0402 exhibits the fold conserved in aminotransferases, and is most similar to that of the Escherichia coli phosphoserine aminotransferase, which belongs to subgroup IV but shares as little as 13% sequence identity with TT0402. Kinetic assays confirmed that TT0402 has higher transamination activities with the amino group donor, L-glutamate, and somewhat lower activities with L-aspartate. These results indicate that TT0402 is a subgroup IV aminotransferase for the synthesis/degradation of either L-aspartate or a similar compound.
+
The line below this paragraph, {{ABSTRACT_PUBMED_15103612}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 15103612 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_15103612}}
==About this Structure==
==About this Structure==
Line 36: Line 40:
[[Category: Structural genomic]]
[[Category: Structural genomic]]
[[Category: Wild type]]
[[Category: Wild type]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 20:25:53 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 14:01:18 2008''

Revision as of 11:01, 1 July 2008

Template:STRUCTURE 1iug

The crystal structure of aspartate aminotransferase which belongs to subgroup IV from Thermus thermophilus

Template:ABSTRACT PUBMED 15103612

About this Structure

1IUG is a Single protein structure of sequence from Thermus thermophilus. Full crystallographic information is available from OCA.

Reference

Crystal structure of a putative aspartate aminotransferase belonging to subgroup IV., Katsura Y, Shirouzu M, Yamaguchi H, Ishitani R, Nureki O, Kuramitsu S, Hayashi H, Yokoyama S, Proteins. 2004 May 15;55(3):487-92. PMID:15103612

Page seeded by OCA on Tue Jul 1 14:01:18 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools