1j4r

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1j4r.gif|left|200px]]
+
{{Seed}}
 +
[[Image:1j4r.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1j4r| PDB=1j4r | SCENE= }}
{{STRUCTURE_1j4r| PDB=1j4r | SCENE= }}
-
'''FK506 BINDING PROTEIN COMPLEXED WITH FKB-001'''
+
===FK506 BINDING PROTEIN COMPLEXED WITH FKB-001===
-
==Overview==
+
<!--
-
[structure: see text] 2-Aryl-2,2-difluoroacetamido-proline and pipecolate esters are high affinity FKBP12 ligands whose rotamase inhibitory activity is comparable to that seen for the corresponding ketoamides. X-ray structural studies suggest that the fluorine atoms participate in discrete interactions with the Phe36 phenyl ring and the Tyr26 hydroxyl group, with the latter resembling a moderate-to-weak hydrogen bond.
+
The line below this paragraph, {{ABSTRACT_PUBMED_11735566}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 11735566 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_11735566}}
==About this Structure==
==About this Structure==
Line 26: Line 30:
[[Category: Inhibitor]]
[[Category: Inhibitor]]
[[Category: Rotamase]]
[[Category: Rotamase]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 20:48:12 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 14:29:58 2008''

Revision as of 11:29, 1 July 2008

Image:1j4r.png

Template:STRUCTURE 1j4r

FK506 BINDING PROTEIN COMPLEXED WITH FKB-001

Template:ABSTRACT PUBMED 11735566

About this Structure

1J4R is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

2-Aryl-2,2-difluoroacetamide FKBP12 ligands: synthesis and X-ray structural studies., Dubowchik GM, Vrudhula VM, Dasgupta B, Ditta J, Chen T, Sheriff S, Sipman K, Witmer M, Tredup J, Vyas DM, Verdoorn TA, Bollini S, Vinitsky A, Org Lett. 2001 Dec 13;3(25):3987-90. PMID:11735566

Page seeded by OCA on Tue Jul 1 14:29:58 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1j4r"
Personal tools