1jmw

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{{STRUCTURE_1jmw| PDB=1jmw | SCENE= }}
{{STRUCTURE_1jmw| PDB=1jmw | SCENE= }}
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'''Propagating Conformational Changes Over Long (And Short) Distances'''
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===Propagating Conformational Changes Over Long (And Short) Distances===
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==Overview==
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The problem of the propagation of conformational changes over long distances or through a closely packed protein is shown to fit a model of a ligand-induced conformational change between two protein states selected by evolution. Moreover, the kinetics of the pathway between these states is also selected so that the energy of ligand binding and the speed of the transition between conformational states are physiologically appropriate. The crystallographic data of a wild-type aspartate receptor that has negative cooperativity and a mutant that has no cooperativity but has native transmembrane signaling are shown to support this model.
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The line below this paragraph, {{ABSTRACT_PUBMED_11504940}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 11504940 is the PubMed ID number.
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{{ABSTRACT_PUBMED_11504940}}
==About this Structure==
==About this Structure==
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[[Category: Bacterial chemotactic receptor]]
[[Category: Bacterial chemotactic receptor]]
[[Category: Chemotaxis]]
[[Category: Chemotaxis]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 21:26:00 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 20:29:12 2008''

Revision as of 17:29, 1 July 2008

Image:1jmw.png

Template:STRUCTURE 1jmw

Propagating Conformational Changes Over Long (And Short) Distances

Template:ABSTRACT PUBMED 11504940

About this Structure

1JMW is a Single protein structure of sequence from Salmonella typhimurium. Full crystallographic information is available from OCA.

Reference

Propagating conformational changes over long (and short) distances in proteins., Yu EW, Koshland DE Jr, Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9517-20. PMID:11504940

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