1k0s

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{{STRUCTURE_1k0s| PDB=1k0s | SCENE= }}
{{STRUCTURE_1k0s| PDB=1k0s | SCENE= }}
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'''Solution structure of the chemotaxis protein CheW from the thermophilic organism Thermotoga maritima'''
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===Solution structure of the chemotaxis protein CheW from the thermophilic organism Thermotoga maritima===
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==Overview==
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Using protein from the hyperthermophile Thermotoga maritima, we have determined the solution structure of CheW, an essential component in the formation of the bacterial chemotaxis signaling complex. The overall fold is similar to the regulatory domain of the chemotaxis kinase CheA. In addition, interactions of CheW with CheA were monitored by nuclear magnetic resonance (NMR) techniques. The chemical shift perturbation data show the probable contacts that CheW makes with CheA. In combination with previous genetic data, the structure also suggests a possible binding site for the chemotaxis receptor. These results provide a structural basis for a model in which CheW acts as a molecular bridge between CheA and the cytoplasmic tails of the receptor.
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{{ABSTRACT_PUBMED_11799399}}
==About this Structure==
==About this Structure==
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1K0S is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K0S OCA].
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1K0S is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K0S OCA].
==Reference==
==Reference==
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[[Category: Zhou, H.]]
[[Category: Zhou, H.]]
[[Category: Chew]]
[[Category: Chew]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 22:09:41 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 21:12:55 2008''

Revision as of 18:12, 1 July 2008

Image:1k0s.png

Template:STRUCTURE 1k0s

Solution structure of the chemotaxis protein CheW from the thermophilic organism Thermotoga maritima

Template:ABSTRACT PUBMED 11799399

About this Structure

1K0S is a Single protein structure of sequence from Thermotoga maritima. Full experimental information is available from OCA.

Reference

The solution structure and interactions of CheW from Thermotoga maritima., Griswold IJ, Zhou H, Matison M, Swanson RV, McIntosh LP, Simon MI, Dahlquist FW, Nat Struct Biol. 2002 Feb;9(2):121-5. PMID:11799399

Page seeded by OCA on Tue Jul 1 21:12:55 2008

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