1ko6

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1ko6.gif|left|200px]]
+
{{Seed}}
 +
[[Image:1ko6.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1ko6| PDB=1ko6 | SCENE= }}
{{STRUCTURE_1ko6| PDB=1ko6 | SCENE= }}
-
'''Crystal Structure of C-terminal Autoproteolytic Domain of Nucleoporin Nup98'''
+
===Crystal Structure of C-terminal Autoproteolytic Domain of Nucleoporin Nup98===
-
==Overview==
+
<!--
-
Nup98 is a component of the nuclear pore that plays its primary role in the export of RNAs. Nup98 is expressed in two forms, derived from alternate mRNA splicing. Both forms are processed into two peptides through autoproteolysis mediated by the C-terminal domain of hNup98. The three-dimensional structure of the C-terminal domain reveals a novel protein fold, and thus a new class of autocatalytic proteases. The structure further reveals that the suggested nucleoporin RNA binding motif is unlikely to bind to RNA. The C terminus also contains sequences that target hNup98 to the nuclear pore complex. Noncovalent interactions between the C-terminal domain and the cleaved peptide tail are visible and suggest a model for cleavage-dependent targeting of hNup98 to the nuclear pore.
+
The line below this paragraph, {{ABSTRACT_PUBMED_12191480}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 12191480 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_12191480}}
==About this Structure==
==About this Structure==
Line 32: Line 36:
[[Category: Nuclear pore]]
[[Category: Nuclear pore]]
[[Category: Nucleoporin]]
[[Category: Nucleoporin]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 22:58:22 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 10:38:10 2008''

Revision as of 07:38, 2 July 2008

Image:1ko6.png

Template:STRUCTURE 1ko6

Crystal Structure of C-terminal Autoproteolytic Domain of Nucleoporin Nup98

Template:ABSTRACT PUBMED 12191480

About this Structure

1KO6 is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

The three-dimensional structure of the autoproteolytic, nuclear pore-targeting domain of the human nucleoporin Nup98., Hodel AE, Hodel MR, Griffis ER, Hennig KA, Ratner GA, Xu S, Powers MA, Mol Cell. 2002 Aug;10(2):347-58. PMID:12191480

Page seeded by OCA on Wed Jul 2 10:38:10 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1ko6"
Personal tools