1lsl

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1lsl.jpg|left|200px]]
+
{{Seed}}
 +
[[Image:1lsl.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1lsl| PDB=1lsl | SCENE= }}
{{STRUCTURE_1lsl| PDB=1lsl | SCENE= }}
-
'''Crystal Structure of the Thrombospondin-1 Type 1 Repeats'''
+
===Crystal Structure of the Thrombospondin-1 Type 1 Repeats===
-
==Overview==
+
<!--
-
Thrombospondin-1 (TSP-1) contains three type 1 repeats (TSRs), which mediate cell attachment, glycosaminoglycan binding, inhibition of angiogenesis, activation of TGFbeta, and inhibition of matrix metalloproteinases. The crystal structure of the TSRs reported in this article reveals a novel, antiparallel, three-stranded fold that consists of alternating stacked layers of tryptophan and arginine residues from respective strands, capped by disulfide bonds on each end. The front face of the TSR contains a right-handed spiral, positively charged groove that might be the "recognition" face, mediating interactions with various ligands. This is the first high-resolution crystal structure of a TSR domain that provides a prototypic architecture for structural and functional exploration of the diverse members of the TSR superfamily.
+
The line below this paragraph, {{ABSTRACT_PUBMED_12391027}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 12391027 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_12391027}}
==About this Structure==
==About this Structure==
Line 32: Line 36:
[[Category: Tsp-1]]
[[Category: Tsp-1]]
[[Category: Tsr]]
[[Category: Tsr]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 00:14:44 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 22:02:50 2008''

Revision as of 19:02, 2 July 2008

Image:1lsl.png

Template:STRUCTURE 1lsl

Crystal Structure of the Thrombospondin-1 Type 1 Repeats

Template:ABSTRACT PUBMED 12391027

About this Structure

1LSL is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Crystal structure of the TSP-1 type 1 repeats: a novel layered fold and its biological implication., Tan K, Duquette M, Liu JH, Dong Y, Zhang R, Joachimiak A, Lawler J, Wang JH, J Cell Biol. 2002 Oct 28;159(2):373-82. Epub 2002 Oct 21. PMID:12391027

Page seeded by OCA on Wed Jul 2 22:02:50 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1lsl"
Personal tools