3cj2
From Proteopedia
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| - | + | ===Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments=== | |
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==About this Structure== | ==About this Structure== | ||
3CJ2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus_subtype_1b Hepatitis c virus subtype 1b]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CJ2 OCA]. | 3CJ2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus_subtype_1b Hepatitis c virus subtype 1b]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CJ2 OCA]. | ||
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| + | ==Reference== | ||
| + | Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors., Antonysamy SS, Aubol B, Blaney J, Browner MF, Giannetti AM, Harris SF, Hebert N, Hendle J, Hopkins S, Jefferson E, Kissinger C, Leveque V, Marciano D, McGee E, Najera I, Nolan B, Tomimoto M, Torres E, Wright T, Bioorg Med Chem Lett. 2008 May 1;18(9):2990-5. Epub 2008 Mar 22. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18400495 18400495] | ||
[[Category: Hepatitis c virus subtype 1b]] | [[Category: Hepatitis c virus subtype 1b]] | ||
[[Category: RNA-directed RNA polymerase]] | [[Category: RNA-directed RNA polymerase]] | ||
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[[Category: Virion]] | [[Category: Virion]] | ||
[[Category: Zinc]] | [[Category: Zinc]] | ||
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Revision as of 19:10, 2 July 2008
Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments
Template:ABSTRACT PUBMED 18400495
About this Structure
3CJ2 is a Single protein structure of sequence from Hepatitis c virus subtype 1b. Full crystallographic information is available from OCA.
Reference
Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors., Antonysamy SS, Aubol B, Blaney J, Browner MF, Giannetti AM, Harris SF, Hebert N, Hendle J, Hopkins S, Jefferson E, Kissinger C, Leveque V, Marciano D, McGee E, Najera I, Nolan B, Tomimoto M, Torres E, Wright T, Bioorg Med Chem Lett. 2008 May 1;18(9):2990-5. Epub 2008 Mar 22. PMID:18400495
Page seeded by OCA on Wed Jul 2 22:10:55 2008
Categories: Hepatitis c virus subtype 1b | RNA-directed RNA polymerase | Single protein | Kissinger, c. | Acetylation | Apoptosis | Atp-binding | Capsid protein | Cytoplasm | Drug discovery | Endoplasmic reticulum | Envelope protein | Fragment based | Fusion protein | Glycoprotein | Hcv ns5b | Helicase | Host-virus interaction | Hydrolase | Interferon antiviral system evasion | Lipid droplet | Lipoprotein | Membrane | Metal-binding | Mitochondrion | Multifunctional enzyme | Nucleotide-binding | Nucleotidyltransferase | Nucleus | Oncogene | Palmitate | Phosphoprotein | Protease | Ribonucleoprotein | Rna replication | Rna-binding | Rna-directed rna polymerase | Secreted | Serine protease | Sh3-binding | Thiol protease | Transcription | Transcription regulation | Transferase | Transmembrane | Ubl conjugation | Viral nucleoprotein | Virion | Zinc
