1lxa

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1lxa.jpg|left|200px]]
+
{{Seed}}
 +
[[Image:1lxa.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1lxa| PDB=1lxa | SCENE= }}
{{STRUCTURE_1lxa| PDB=1lxa | SCENE= }}
-
'''UDP N-ACETYLGLUCOSAMINE ACYLTRANSFERASE'''
+
===UDP N-ACETYLGLUCOSAMINE ACYLTRANSFERASE===
-
==Overview==
+
<!--
-
UDP-N-acetylglucosamine 3-O-acyltransferase (LpxA) catalyzes the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-N-acetylglucosamine. LpxA is the first enzyme in the lipid A biosynthetic pathway and is a target for the design of antibiotics. The x-ray crystal structure of LpxA has been determined to 2.6 angstrom resolution and reveals a domain motif composed of parallel beta strands, termed a left-handed parallel beta helix (L beta H). This unusual fold displays repeated violations of the protein folding constraint requiring right-handed crossover connections between strands of parallel beta sheets and may be present in other enzymes that share amino acid sequence homology to the repeated hexapeptide motif of LpxA.
+
The line below this paragraph, {{ABSTRACT_PUBMED_7481807}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 7481807 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_7481807}}
==About this Structure==
==About this Structure==
Line 27: Line 31:
[[Category: Lipid synthesis]]
[[Category: Lipid synthesis]]
[[Category: Transferase]]
[[Category: Transferase]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 00:23:25 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 22:45:13 2008''

Revision as of 19:45, 2 July 2008

Image:1lxa.png

Template:STRUCTURE 1lxa

UDP N-ACETYLGLUCOSAMINE ACYLTRANSFERASE

Template:ABSTRACT PUBMED 7481807

About this Structure

1LXA is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

A left-handed parallel beta helix in the structure of UDP-N-acetylglucosamine acyltransferase., Raetz CR, Roderick SL, Science. 1995 Nov 10;270(5238):997-1000. PMID:7481807

Page seeded by OCA on Wed Jul 2 22:45:13 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1lxa"
Personal tools