1lxd

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{{STRUCTURE_1lxd| PDB=1lxd | SCENE= }}
{{STRUCTURE_1lxd| PDB=1lxd | SCENE= }}
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'''CRYSTAL STRUCTURE OF THE RAS INTERACTING DOMAIN OF RALGDS, A GUANINE NUCLEOTIDE DISSOCIATION STIMULATOR OF RAL PROTEIN'''
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===CRYSTAL STRUCTURE OF THE RAS INTERACTING DOMAIN OF RALGDS, A GUANINE NUCLEOTIDE DISSOCIATION STIMULATOR OF RAL PROTEIN===
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==Overview==
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The Ras-interacting domains of the the protein-kinase Raf and the Ral guanine nucleotide dissociation stimulator, RalGDS, lack extensive sequence similarity, but their overall three-dimensional structures are very similar to each other. Mutational analysis indicated that three residues in the RalGDS domain are critical for its interaction with Ras.
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(as it appears on PubMed at http://www.pubmed.gov), where 9253406 is the PubMed ID number.
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{{ABSTRACT_PUBMED_9253406}}
==About this Structure==
==About this Structure==
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[[Category: Signal transduction]]
[[Category: Signal transduction]]
[[Category: Ubiquitin fold]]
[[Category: Ubiquitin fold]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 00:23:32 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 22:45:22 2008''

Revision as of 19:45, 2 July 2008

Template:STRUCTURE 1lxd

CRYSTAL STRUCTURE OF THE RAS INTERACTING DOMAIN OF RALGDS, A GUANINE NUCLEOTIDE DISSOCIATION STIMULATOR OF RAL PROTEIN

Template:ABSTRACT PUBMED 9253406

About this Structure

1LXD is a Single protein structure of sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

Three-dimensional structure of the Ras-interacting domain of RalGDS., Huang L, Weng X, Hofer F, Martin GS, Kim SH, Nat Struct Biol. 1997 Aug;4(8):609-15. PMID:9253406

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