1lzt

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[[Image:1lzt.gif|left|200px]]
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{{Seed}}
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[[Image:1lzt.png|left|200px]]
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{{STRUCTURE_1lzt| PDB=1lzt | SCENE= }}
{{STRUCTURE_1lzt| PDB=1lzt | SCENE= }}
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'''REFINEMENT OF TRICLINIC LYSOZYME'''
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===REFINEMENT OF TRICLINIC LYSOZYME===
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==Overview==
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X-ray diffraction data to 1.5 A resolution have been collected for triclinic crystals of hen egg white lysozyme. The triclinic model was derived from the tetragonal one by the rotation function and refined initially by Fo-Fc and differential difference syntheses against 2 A resolution data. Refinement was continued by differential difference cycles against the 1.5 A data until R was reduced to 0.220. Although the initial refinement was rapid, it was subsequently a matter of attrition, leading to a complete recheck of the data and the discovery of systematic error which affected primarily the high-resolution data. Refinement was continued against the corrected 2 A data by block-diagonal least squares. After five cycles the refinement was terminated at R = 0.254 because of the imminent availability of a preferred refinement program. Problems with the protein model, the solvent, and the interaction of the scale and thermal parameters are discussed. The experiences gained in this study are summarized.
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The line below this paragraph, {{ABSTRACT_PUBMED_2302326}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 2302326 is the PubMed ID number.
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{{ABSTRACT_PUBMED_2302326}}
==About this Structure==
==About this Structure==
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[[Category: Jensen, L H.]]
[[Category: Jensen, L H.]]
[[Category: Sieker, L C.]]
[[Category: Sieker, L C.]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 00:27:39 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 22:54:06 2008''

Revision as of 19:54, 2 July 2008

Template:STRUCTURE 1lzt

REFINEMENT OF TRICLINIC LYSOZYME

Template:ABSTRACT PUBMED 2302326

About this Structure

1LZT is a Single protein structure of sequence from Gallus gallus. Full crystallographic information is available from OCA.

Reference

Refinement of triclinic lysozyme: I. Fourier and least-squares methods., Hodsdon JM, Brown GM, Sieker LC, Jensen LH, Acta Crystallogr B. 1990 Feb 1;46 ( Pt 1):54-62. PMID:2302326

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