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1m42

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{{STRUCTURE_1m42| PDB=1m42 | SCENE= }}
{{STRUCTURE_1m42| PDB=1m42 | SCENE= }}
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'''Solution structure of apoCopC from Pseudomonas syringae'''
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===Solution structure of apoCopC from Pseudomonas syringae===
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==Overview==
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The structure of the metal-free form of CopC, a protein involved in copper homeostasis, has been obtained. The fold is a Greek key beta barrel similar to that of functionally unrelated blue copper proteins but with important structural variations. The protein binds one equivalent of copper (II) with relatively high affinity and contains a cluster of conserved residues (His1, Glu27, Asp89, and His91) which could form a water-accessible metal binding site. The structure also reveals a loop containing the M(X)(n)M motif which is present in a number of proteins also involved in copper homeostasis. The present structure represents a link between copper-trafficking proteins and cupredoxins. Within a structural and genomic analysis, the role of CopC in copper trafficking is discussed.
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(as it appears on PubMed at http://www.pubmed.gov), where 12377120 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12377120}}
==About this Structure==
==About this Structure==
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1M42 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_syringae Pseudomonas syringae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M42 OCA].
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1M42 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_syringae Pseudomonas syringae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M42 OCA].
==Reference==
==Reference==
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[[Category: Copper trafficking]]
[[Category: Copper trafficking]]
[[Category: Cupredoxin]]
[[Category: Cupredoxin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 00:36:07 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 23:09:46 2008''

Revision as of 20:09, 2 July 2008

Image:1m42.png

Template:STRUCTURE 1m42

Solution structure of apoCopC from Pseudomonas syringae

Template:ABSTRACT PUBMED 12377120

About this Structure

1M42 is a Single protein structure of sequence from Pseudomonas syringae. Full experimental information is available from OCA.

Reference

Solution structure of CopC: a cupredoxin-like protein involved in copper homeostasis., Arnesano F, Banci L, Bertini I, Thompsett AR, Structure. 2002 Oct;10(10):1337-47. PMID:12377120

Page seeded by OCA on Wed Jul 2 23:09:46 2008

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