1mal

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{{STRUCTURE_1mal| PDB=1mal | SCENE= }}
{{STRUCTURE_1mal| PDB=1mal | SCENE= }}
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'''STRUCTURAL BASIS FOR SUGAR TRANSLOCATION THROUGH MALTOPORIN CHANNELS AT 3.1 ANGSTROMS RESOLUTION'''
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===STRUCTURAL BASIS FOR SUGAR TRANSLOCATION THROUGH MALTOPORIN CHANNELS AT 3.1 ANGSTROMS RESOLUTION===
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==Overview==
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Trimeric maltoporin (LamB protein) facilitates the diffusion of maltodextrins across the outer membrane of Gram-negative bacteria. The crystal structure of maltoporin from Escherichia coli, determined to a resolution of 3.1 angstroms, reveals an 18-stranded, antiparallel beta-barrel that forms the framework of the channel. Three inwardly folded loops contribute to a constriction about halfway through the channel. Six contingent aromatic residues line the channel and form a path from the vestibule to the periplasmic outlet. Soaking of a crystal with maltotriose revealed binding of the sugar to this hydrophobic track across the constriction, which suggests that maltose and linear oligosaccharides may be translocated across the membrane by guided diffusion along this path.
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(as it appears on PubMed at http://www.pubmed.gov), where 7824948 is the PubMed ID number.
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{{ABSTRACT_PUBMED_7824948}}
==About this Structure==
==About this Structure==
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[[Category: Schirmer, T.]]
[[Category: Schirmer, T.]]
[[Category: Outer membrane protein]]
[[Category: Outer membrane protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 00:49:54 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 23:34:12 2008''

Revision as of 20:34, 2 July 2008

Template:STRUCTURE 1mal

STRUCTURAL BASIS FOR SUGAR TRANSLOCATION THROUGH MALTOPORIN CHANNELS AT 3.1 ANGSTROMS RESOLUTION

Template:ABSTRACT PUBMED 7824948

About this Structure

1MAL is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

Structural basis for sugar translocation through maltoporin channels at 3.1 A resolution., Schirmer T, Keller TA, Wang YF, Rosenbusch JP, Science. 1995 Jan 27;267(5197):512-4. PMID:7824948

Page seeded by OCA on Wed Jul 2 23:34:12 2008

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