1me4

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1me4.jpg|left|200px]]
+
{{Seed}}
 +
[[Image:1me4.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1me4| PDB=1me4 | SCENE= }}
{{STRUCTURE_1me4| PDB=1me4 | SCENE= }}
-
'''High Resolution Crystal Structure Analysis Of Cruzain non-covalently Bound To A Hydroxymethyl Ketone Inhibitor (I)'''
+
===High Resolution Crystal Structure Analysis Of Cruzain non-covalently Bound To A Hydroxymethyl Ketone Inhibitor (I)===
-
==Overview==
+
<!--
-
The crystal structures of two hydroxymethyl ketone inhibitors complexed to the cysteine protease cruzain have been determined at 1.1 and 1.2 A resolution, respectively. These high resolution crystal structures provide the first structures of non-covalent inhibitors bound to cruzain. A series of compounds were prepared and tested based upon the structures providing further insight into the key binding interactions.
+
The line below this paragraph, {{ABSTRACT_PUBMED_12467703}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 12467703 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_12467703}}
==About this Structure==
==About this Structure==
Line 27: Line 31:
[[Category: Cysteine protease]]
[[Category: Cysteine protease]]
[[Category: Non-covalent inhibitor]]
[[Category: Non-covalent inhibitor]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 00:55:57 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 23:46:23 2008''

Revision as of 20:46, 2 July 2008

Image:1me4.png

Template:STRUCTURE 1me4

High Resolution Crystal Structure Analysis Of Cruzain non-covalently Bound To A Hydroxymethyl Ketone Inhibitor (I)

Template:ABSTRACT PUBMED 12467703

About this Structure

1ME4 is a Single protein structure of sequence from Trypanosoma cruzi. Full crystallographic information is available from OCA.

Reference

Crystal structures of reversible ketone-Based inhibitors of the cysteine protease cruzain., Huang L, Brinen LS, Ellman JA, Bioorg Med Chem. 2003 Jan 2;11(1):21-9. PMID:12467703

Page seeded by OCA on Wed Jul 2 23:46:23 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1me4"
Personal tools