1mom

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[[Image:1mom.jpg|left|200px]]
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{{Seed}}
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[[Image:1mom.png|left|200px]]
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{{STRUCTURE_1mom| PDB=1mom | SCENE= }}
{{STRUCTURE_1mom| PDB=1mom | SCENE= }}
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'''CRYSTAL STRUCTURE OF MOMORDIN, A TYPE I RIBOSOME INACTIVATING PROTEIN FROM THE SEEDS OF MOMORDICA CHARANTIA'''
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===CRYSTAL STRUCTURE OF MOMORDIN, A TYPE I RIBOSOME INACTIVATING PROTEIN FROM THE SEEDS OF MOMORDICA CHARANTIA===
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==Overview==
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A type I ribosome-inactivating protein, extracted and purified from M. charantia seeds, was crystallised by vapour diffusion with polyethylene glycol at pH 7.2. X-ray data were collected to 2.1 A resolution and the structure solved by molecular replacement using the A-chain coordinates of ricin. The overall fold of the protein is similar to ricin but there are differences in secondary structure, on the surface and in the active site cleft. These differences are probably due in part to the evolution of the protein without a B-chain partner. The most extensive reorganisation occurs at the C-terminus whereas Tyr70 shows the greatest change in the active site cleft.
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The line below this paragraph, {{ABSTRACT_PUBMED_8143869}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 8143869 is the PubMed ID number.
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{{ABSTRACT_PUBMED_8143869}}
==About this Structure==
==About this Structure==
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[[Category: Tickle, I J.]]
[[Category: Tickle, I J.]]
[[Category: Wood, S P.]]
[[Category: Wood, S P.]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 01:31:43 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jul 3 00:35:08 2008''

Revision as of 21:35, 2 July 2008

Image:1mom.png

Template:STRUCTURE 1mom

CRYSTAL STRUCTURE OF MOMORDIN, A TYPE I RIBOSOME INACTIVATING PROTEIN FROM THE SEEDS OF MOMORDICA CHARANTIA

Template:ABSTRACT PUBMED 8143869

About this Structure

1MOM is a Single protein structure. Full crystallographic information is available from OCA.

Reference

Crystal structure of momordin, a type I ribosome inactivating protein from the seeds of Momordica charantia., Husain J, Tickle IJ, Wood SP, FEBS Lett. 1994 Apr 4;342(2):154-8. PMID:8143869

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