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3por

From Proteopedia

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[[Image:3por.jpg|left|200px]]
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{{STRUCTURE_3por| PDB=3por | SCENE= }}
{{STRUCTURE_3por| PDB=3por | SCENE= }}
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'''PORIN CONFORMATION IN THE ABSENCE OF CALCIUM; REFINED STRUCTURE AT 2.5 ANGSTROMS RESOLUTION'''
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===PORIN CONFORMATION IN THE ABSENCE OF CALCIUM; REFINED STRUCTURE AT 2.5 ANGSTROMS RESOLUTION===
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==Overview==
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The crystal structure of porin from Rhodobacter capsulatus in the absence of divalent calcium ions has been refined to convergence at a resolution of 2.5 A using the simulated annealing refinement method. The final model consists of all 301 amino acid residues, 77 solvent molecules, one tris(hydroxymethyl)-aminomethane molecule and one unknown ligand modeled as n-octyltetraoxyethylene. A superposition with the previously described model containing three calcium ions showed structural changes at the segment 108-116 of the inner loop beta 5-beta 6, and at loops beta 8-beta 9 and beta 11-beta 12 at the extracellular side of the porin molecule. Evidence is presented that the conformational changes depend on the presence or absence of calcium ions. A possible influence on porin function is discussed.
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(as it appears on PubMed at http://www.pubmed.gov), where 7685826 is the PubMed ID number.
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{{ABSTRACT_PUBMED_7685826}}
==About this Structure==
==About this Structure==
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[[Category: Weiss, M S.]]
[[Category: Weiss, M S.]]
[[Category: Integral membrane protein porin]]
[[Category: Integral membrane protein porin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 22:10:54 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jul 3 13:02:52 2008''

Revision as of 10:02, 3 July 2008

Image:3por.png

Template:STRUCTURE 3por

PORIN CONFORMATION IN THE ABSENCE OF CALCIUM; REFINED STRUCTURE AT 2.5 ANGSTROMS RESOLUTION

Template:ABSTRACT PUBMED 7685826

About this Structure

3POR is a Single protein structure of sequence from Rhodobacter capsulatus. Full crystallographic information is available from OCA.

Reference

Porin conformation in the absence of calcium. Refined structure at 2.5 A resolution., Weiss MS, Schulz GE, J Mol Biol. 1993 Jun 5;231(3):817-24. PMID:7685826

Page seeded by OCA on Thu Jul 3 13:02:52 2008

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