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3ull

From Proteopedia

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{{STRUCTURE_3ull| PDB=3ull | SCENE= }}
{{STRUCTURE_3ull| PDB=3ull | SCENE= }}
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'''HUMAN MITOCHONDRIAL SINGLE-STRANDED DNA BINDING PROTEIN'''
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===HUMAN MITOCHONDRIAL SINGLE-STRANDED DNA BINDING PROTEIN===
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==Overview==
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We solved the crystal structure of the homotetrameric single-stranded DNA binding (SSB) protein from human mitochondria at a resolution of 2.4 A. The tetramer is formed by two dimers interacting head-to-head and shows D2 symmetry. Sequence-related tetrameric SSB proteins occur in prokaryotes and eukaryotic mitochondria; this is the first report of an atomic resolution structure of this type of protein. Using biochemical data and analysis of sequence homologies, we were able to correlate the functional properties with structure. We propose that ssDNA wraps around the tetrameric HsmtSSB protein through electropositive channels guided by flexible loops.
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(as it appears on PubMed at http://www.pubmed.gov), where 9033597 is the PubMed ID number.
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{{ABSTRACT_PUBMED_9033597}}
==About this Structure==
==About this Structure==
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[[Category: Mitochondrion]]
[[Category: Mitochondrion]]
[[Category: Transit peptide]]
[[Category: Transit peptide]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 22:14:57 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jul 3 13:11:12 2008''

Revision as of 10:11, 3 July 2008

Image:3ull.png

Template:STRUCTURE 3ull

HUMAN MITOCHONDRIAL SINGLE-STRANDED DNA BINDING PROTEIN

Template:ABSTRACT PUBMED 9033597

About this Structure

3ULL is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Crystal structure of human mitochondrial single-stranded DNA binding protein at 2.4 A resolution., Yang C, Curth U, Urbanke C, Kang C, Nat Struct Biol. 1997 Feb;4(2):153-7. PMID:9033597

Page seeded by OCA on Thu Jul 3 13:11:12 2008

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