402d

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[[Image:402d.gif|left|200px]]
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{{STRUCTURE_402d| PDB=402d | SCENE= }}
{{STRUCTURE_402d| PDB=402d | SCENE= }}
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'''5'-R(*CP*GP*CP*CP*AP*GP*CP*G)-3''''
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===5'-R(*CP*GP*CP*CP*AP*GP*CP*G)-3'===
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==Overview==
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The crystal structure of the RNA octamer 5'-CGC(CA)GCG-3' has been determined from X-ray diffraction data to 2.3 A resolution. In the crystal, this oligomer forms a self-complementary double helix in the asymmetric unit. Tandem non-Watson-Crick C-A and A-C base pairs comprise an internal loop in the middle of the duplex, which is incorporated with little distortion of the A-form double helix. From the geometry of the C-A base pairs, it is inferred that the adenosine imino group is protonated and donates a hydrogen bond to the carbonyl group of the cytosine. The wobble geometry of the C-A+ base pairs is very similar to that of the common U-G non-Watson-Crick pair.
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(as it appears on PubMed at http://www.pubmed.gov), where 9718295 is the PubMed ID number.
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{{ABSTRACT_PUBMED_9718295}}
==About this Structure==
==About this Structure==
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[[Category: Rna double helix]]
[[Category: Rna double helix]]
[[Category: Rna with tandem c-a+ base pair]]
[[Category: Rna with tandem c-a+ base pair]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 22:16:06 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jul 3 13:14:34 2008''

Revision as of 10:14, 3 July 2008

Image:402d.png

Template:STRUCTURE 402d

5'-R(*CP*GP*CP*CP*AP*GP*CP*G)-3'

Template:ABSTRACT PUBMED 9718295

About this Structure

Full crystallographic information is available from OCA.

Reference

Structure of an RNA internal loop consisting of tandem C-A+ base pairs., Jang SB, Hung LW, Chi YI, Holbrook EL, Carter RJ, Holbrook SR, Biochemistry. 1998 Aug 25;37(34):11726-31. PMID:9718295

Page seeded by OCA on Thu Jul 3 13:14:34 2008

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