426d

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{{STRUCTURE_426d| PDB=426d | SCENE= }}
{{STRUCTURE_426d| PDB=426d | SCENE= }}
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'''THE STRUCTURE OF MOST STUDIED DNA FRAGMENT CHANGES UNDER THE INFLUENCE OF IONS: A NEW PACKING OF D(CGCGAATTCGCG)'''
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===THE STRUCTURE OF MOST STUDIED DNA FRAGMENT CHANGES UNDER THE INFLUENCE OF IONS: A NEW PACKING OF D(CGCGAATTCGCG)===
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==Overview==
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The title oligonucleotide and many related dodecamers have been extensively studied alone and as DNA-drug complexes. In practically all cases they were found to crystallize in the same space group, stabilized by interactions among the terminal guanine bases. Here we report new packing interactions (R3) in the presence of Ca2+. The oligonucleotides interact by placing their terminal guanines in the narrow groove of a neighbor molecule, an interaction which had never been found in dodecamers.
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The line below this paragraph, {{ABSTRACT_PUBMED_9827547}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 9827547 is the PubMed ID number.
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{{ABSTRACT_PUBMED_9827547}}
==About this Structure==
==About this Structure==
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[[Category: Subirana, J A.]]
[[Category: Subirana, J A.]]
[[Category: Double helix]]
[[Category: Double helix]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jul 3 13:17:54 2008''

Revision as of 10:17, 3 July 2008

Template:STRUCTURE 426d

THE STRUCTURE OF MOST STUDIED DNA FRAGMENT CHANGES UNDER THE INFLUENCE OF IONS: A NEW PACKING OF D(CGCGAATTCGCG)

Template:ABSTRACT PUBMED 9827547

About this Structure

Full crystallographic information is available from OCA.

Reference

The structure of the most studied DNA fragment changes under the influence of ions: a new packing of d(CGCGAATTCGCG)., Liu J, Malinina L, Huynh-Dinh T, Subirana JA, FEBS Lett. 1998 Nov 6;438(3):211-4. PMID:9827547

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