486d

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[[Image:486d.gif|left|200px]]
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{{STRUCTURE_486d| PDB=486d | SCENE= }}
{{STRUCTURE_486d| PDB=486d | SCENE= }}
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'''X-RAY CRYSTAL STRUCTURES OF 70S RIBOSOME FUNCTIONAL COMPLEXES'''
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===X-RAY CRYSTAL STRUCTURES OF 70S RIBOSOME FUNCTIONAL COMPLEXES===
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==Overview==
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Structures of 70S ribosome complexes containing messenger RNA and transfer RNA (tRNA), or tRNA analogs, have been solved by x-ray crystallography at up to 7.8 angstrom resolution. Many details of the interactions between tRNA and the ribosome, and of the packing arrangements of ribosomal RNA (rRNA) helices in and between the ribosomal subunits, can be seen. Numerous contacts are made between the 30S subunit and the P-tRNA anticodon stem-loop; in contrast, the anticodon region of A-tRNA is much more exposed. A complex network of molecular interactions suggestive of a functional relay is centered around the long penultimate stem of 16S rRNA at the subunit interface, including interactions involving the "switch" helix and decoding site of 16S rRNA, and RNA bridges from the 50S subunit.
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(as it appears on PubMed at http://www.pubmed.gov), where 10497122 is the PubMed ID number.
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{{ABSTRACT_PUBMED_10497122}}
==About this Structure==
==About this Structure==
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[[Category: Functional models of 70s ribosome]]
[[Category: Functional models of 70s ribosome]]
[[Category: Trna]]
[[Category: Trna]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 22:20:05 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jul 3 13:26:30 2008''

Revision as of 10:26, 3 July 2008

Image:486d.png

Template:STRUCTURE 486d

X-RAY CRYSTAL STRUCTURES OF 70S RIBOSOME FUNCTIONAL COMPLEXES

Template:ABSTRACT PUBMED 10497122

About this Structure

Full crystallographic information is available from OCA.

Reference

X-ray crystal structures of 70S ribosome functional complexes., Cate JH, Yusupov MM, Yusupova GZ, Earnest TN, Noller HF, Science. 1999 Sep 24;285(5436):2095-104. PMID:10497122

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